受污染的Descemet膜内皮角膜移植片移植后发生痤疮丙酸杆菌性眼内炎。
Propionibacterium acnes endophthalmitis following transplantation of contaminated Descemet's membrane endothelial keratoplasty graft.
作者信息
Armstrong Grayson W, Lin Shawn R, Assidon Aviram, Soukiasian Sarkis, Eliott Dean, Jurkunas Ula
机构信息
Department of Ophthalmology, Massachusetts Eye & Ear, 243 Charles St, Boston, MA, 02114, USA.
Department of General Surgery, 291 Campus Drive, Stanford University, Palo Alto, CA, 94305, USA.
出版信息
Am J Ophthalmol Case Rep. 2021 Oct 27;24:101227. doi: 10.1016/j.ajoc.2021.101227. eCollection 2021 Dec.
PURPOSE
To report the clinical outcomes of a case of Propionibacterium acnes (P. acnes) endophthalmitis following Descemet's membrane endothelial keratoplasty (DMEK) surgery.
OBSERVATIONS
Transplantation of non-sterile DMEK tissue led to development of a retrolenticular white plaque confirmed through PCR testing to be the result of P. acnes endophthalmitis. Intraocular antimicrobial therapy, surgical scraping of the white plaque, and repeat DMEK tissue transplantation resulted in an excellent visual outcome (20/20).
CONCLUSION
This is the first reported case of P. acnes endophthalmitis following DMEK surgery. Re-transplantation may be a viable option for DMEK patients who experience post-operative endophthalmitis.
目的
报告1例在Descemet膜内皮角膜移植术（DMEK）后发生痤疮丙酸杆菌（P. acnes）性眼内炎的临床结果。
观察结果
非无菌DMEK组织移植导致晶状体后出现白色斑块，经聚合酶链反应（PCR）检测证实为痤疮丙酸杆菌性眼内炎。眼内抗菌治疗、手术刮除白色斑块以及再次进行DMEK组织移植，最终获得了极佳的视力结果（20/20）。
结论
这是首例报道的DMEK手术后发生痤疮丙酸杆菌性眼内炎的病例。对于术后发生眼内炎的DMEK患者，再次移植可能是一种可行的选择。
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