Manankandayalage Chamila P, Unruh Daniel K, Krempner Clemens
Department of Chemistry and Biochemistry, Texas Tech University, Memorial Dr & Boston, Lubbock, TX, 79409, USA.
Chem Commun (Camb). 2021 Nov 23;57(93):12528-12531. doi: 10.1039/d1cc05673e.
Utilizing an intramolecular frustrated Lewis pair (FLP) decorated with a strongly donating guanidino moiety enabled the formation of a thermally remarkably stable FLP-CO adduct, which at 120 °C underwent CO migration to form an acyl borane. Both compounds underwent rapid CO cleavage in the presence of strong electrophiles leading to the selective formation of a range of new 1,2- and 1,3-benzazaboroles in good yields under mild conditions.
利用一个带有强给电子胍基部分修饰的分子内受阻路易斯对（FLP）能够形成一种热稳定性极高的FLP-CO加合物，该加合物在120℃下会发生CO迁移形成酰基硼烷。这两种化合物在强亲电试剂存在下均能快速发生CO裂解，从而在温和条件下以良好的产率选择性地形成一系列新型1,2-和1,3-苯并氮杂硼烷。
