Department of Otorhinolaryngology Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing, China.
World J Pediatr. 2021 Dec;17(6):637-642. doi: 10.1007/s12519-021-00471-8. Epub 2021 Nov 12.
This study aimed to evaluate the relationship between vestibular and auditory functions in pediatric patients with sudden sensorineural hearing loss (SSHL).
A total of 30 pediatric patients experiencing unilateral SSHL between 5.9 and 13.0 years of age were enrolled in this study. Pure tone audiometry was evaluated prior to treatment initiation and again after one month of treatment. Prior to treatment initiation, vertigo symptoms were noted; then several vestibular function tests were conducted including caloric testing, ocular vestibular evoked myogenic potentials (o-VEMPs) and cervical vestibular evoked myogenic potentials (c-VEMPs). Associations between pre and post-treatment vestibular function and hearing threshold levels were analyzed.
Initial hearing thresholds of children with vertigo were higher than thresholds of children without vertigo (92 dB vs 79 dB, P = 0.033), while initial hearing thresholds of children with abnormal caloric test findings were higher than thresholds of children with normal caloric test findings (93 dB vs 67 dB, P = 0.014). Cutoff values of hearing thresholds for those with vertigo symptoms and abnormal vestibular test results were 86.000- and 89.583-dB HL, respectively. Regarding prognosis, children with vertigo exhibited lower recovery rates than children without vertigo (33% vs 75%, P = 0.025); recovery rates of children with abnormal caloric test results were lower than the overall recovery rate (25% vs 73%, respectively, P = 0.039).
Assessments of vertigo symptoms and vestibular function are useful tools in predicting pediatric SSHL patient disease severity and prognosis.
本研究旨在评估儿童突发性聋（SSHL）患者前庭和听觉功能之间的关系。
本研究纳入了 30 名年龄在 5.9 至 13.0 岁之间单侧发生 SSHL 的儿科患者。在开始治疗前和治疗一个月后进行纯音测听。在开始治疗前，记录眩晕症状；然后进行了几项前庭功能测试，包括冷热试验、眼震电图（o-VEMP）和颈肌前庭诱发肌源性电位（c-VEMP）。分析了治疗前后前庭功能与听力阈值水平之间的关系。
有眩晕症状的儿童的初始听力阈值高于无眩晕症状的儿童（92dB 与 79dB，P=0.033），而冷热试验异常的儿童的初始听力阈值高于冷热试验正常的儿童（93dB 与 67dB，P=0.014）。有眩晕症状和异常前庭测试结果的儿童的听力阈值截断值分别为 86.000 和 89.583dB HL。就预后而言，有眩晕症状的儿童的恢复率低于无眩晕症状的儿童（33%与 75%，P=0.025）；冷热试验异常的儿童的恢复率低于总体恢复率（25%与 73%，P=0.039）。
评估眩晕症状和前庭功能是预测儿科 SSHL 患者疾病严重程度和预后的有用工具。
