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超声引导下双侧竖脊肌平面连续阻滞与心脏直视手术中阿片类药物消耗量减少及住院时间缩短相关:一项回顾性队列研究。

Ultrasound-Guided Continuous Bilateral Erector Spinae Plane Blocks Are Associated with Reduced Opioid Consumption and Length of Stay for Open Cardiac Surgery: A Retrospective Cohort Study.

作者信息

Vaughan Brian N, Bartone Cheryl L, McCarthy Catherine M, Answini Geoffrey A, Hurford William E

机构信息

Department of Anesthesiology, University of Cincinnati, Cincinnati, OH 45267, USA.

The Christ Hospital Health Network, Heart and Vascular Services, Cincinnati, OH 45219, USA.

出版信息

J Clin Med. 2021 Oct 28;10(21):5022. doi: 10.3390/jcm10215022.

Abstract

This study tested the hypothesis that continuous bilateral erector spinae plane blocks placed preoperatively would reduce opioid consumption and improve outcomes compared with standard practice in open cardiac surgery patients. Patients who received bilateral continuous erector spinae plane blocks for primary open coronary bypass, aortic valve, or ascending aortic surgery were compared to a historical control group. Patients in the block group received a 0.5% ropivacaine bolus preoperatively followed by a 0.2% ropivacaine infusion begun postoperatively. No other changes were made to the perioperative care protocol. The primary outcome was opioid consumption. Secondary outcomes were time to extubation and length of stay. Twenty-eight patients received continuous erector spinae plane blocks and fifty patients served as historic controls. Patients who received blocks consumed less opioids, expressed as oral morphine equivalents, both intraoperatively (34 ± 17 vs. 224 ± 125 mg) and during their hospitalization (224 ± 108 vs. 461 ± 185 mg). Patients who received blocks had shorter times to extubation (126 ± 87 vs. 257 ± 188 min) and lengths of stay in the intensive care unit (35 ± 17 vs. 58 ± 42 h) and hospital (5.6 ± 1.6 vs. 7.7 ± 4.6 days). Continuous erector spinae plane blocks placed prior to open cardiac surgical procedures reduced opioid consumption, time to extubation, and length of stay compared to a standard perioperative pathway.

摘要

本研究检验了以下假设

与心脏直视手术患者的标准治疗方法相比,术前放置双侧竖脊肌平面连续阻滞可减少阿片类药物的使用并改善预后。将接受双侧竖脊肌平面连续阻滞用于初次心脏直视冠状动脉搭桥术、主动脉瓣手术或升主动脉手术的患者与一个历史对照组进行比较。阻滞组患者术前接受0.5%罗哌卡因推注,术后开始输注0.2%罗哌卡因。围手术期护理方案未作其他更改。主要结局是阿片类药物的使用量。次要结局是拔管时间和住院时间。28例患者接受了竖脊肌平面连续阻滞,50例患者作为历史对照。接受阻滞的患者术中(34±17 vs. 224±125 mg)和住院期间(224±108 vs. 461±185 mg)以口服吗啡当量表示的阿片类药物消耗量较少。接受阻滞的患者拔管时间较短(126±87 vs. 257±188分钟),重症监护病房住院时间较短(35±17 vs. 58±42小时),住院时间较短(5.6±1.6 vs. 7.7±4.6天)。与标准围手术期治疗路径相比,心脏直视手术前放置双侧竖脊肌平面连续阻滞可减少阿片类药物的使用量、拔管时间和住院时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c1a/8584924/9933e71ae4a8/jcm-10-05022-g001.jpg

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