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雄性洪都拉斯白脸卷尾猴(Cebus albifrons)自发性乳腺肿瘤的组织病理学和免疫表型特征。

Histopathologic and immunophenotypic profile of a spontaneous mammary carcinoma in a male Humboldt's white-fronted capuchin (Cebus albifrons).

机构信息

Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Instituto de Ciências Biológicas, Departamento de Patologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

出版信息

J Med Primatol. 2022 Feb;51(1):49-52. doi: 10.1111/jmp.12553. Epub 2021 Nov 12.

Abstract

A 20-year-old male captive Humboldt's white-fronted capuchin (Cebus albifrons) that died accidentally had a small non-ulcerative mammary nodule diagnosed as a mammary carcinoma. Immunohistochemistry demonstrated that neoplastic cells were positive for pan-cytokeratin and cytokeratin-7. Approximately 20% of neoplastic cells were positive for Ki-67. Neoplastic cells expressed estrogen and progesterone receptors.

摘要

一只 20 岁的雄性人工饲养的洪都拉斯白脸卷尾猴(Cebus albifrons)意外死亡,其乳房有一个小的非溃疡性结节,被诊断为乳腺癌。免疫组织化学显示,肿瘤细胞对广谱细胞角蛋白和细胞角蛋白-7呈阳性。大约 20%的肿瘤细胞对 Ki-67 呈阳性。肿瘤细胞表达雌激素和孕激素受体。

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