Saini Nidhi, Lather Viney, Gahlawat Suresh Kumar
Department of Biotechnology, Chaudhary Devi Lal University, Sirsa 125055, India.
Department of Pharmaceutical, Amity University, Noida, India.
Anticancer Agents Med Chem. 2022;22(9):1674-1698. doi: 10.2174/1871520621666211015141020.
Over-prescription of medicines leads to some crucial health issues like resistance, non-specificity, etc. Therefore, a human consumes various natural foods, therapeutics, and nutritional supplements to combat this problem. Various therapeutic properties of secondary metabolites, such as anticancer, anti-inflammatory, and antibacterial properties, are important in drug discovery and medicinal application. These natural products have replaced synthetic materials, resulting in a great deal of sustainability, rational use, and preservation of biodiversity. This review described the potential therapeutic applications of secondary plant metabolites found in Himalayan Indian plants. The database contains 45 plants to treat various diseases, such as cancer, inflammation, and microbial infections. Besides authorized ITIS names, it includes Hindi names, family names, and active constituents. The most important information about the molecules can be found in the hyperlinks for the active constituents. It includes structures (two-dimensional and threedimensional), names and identifiers, chemical and physical properties, spectral information, biochemistry, literature and patents. The review also references various phytochemicals responsible for preventing COVID-19. Despite several challenges in manufacturing natural products, researchers may conduct research to produce successful medicines with few side effects.
药物的过度处方会导致一些关键的健康问题，如抗药性、非特异性等。因此，人们食用各种天然食物、治疗药物和营养补充剂来应对这一问题。次生代谢产物的各种治疗特性，如抗癌、抗炎和抗菌特性，在药物发现和医学应用中很重要。这些天然产物已经取代了合成材料，带来了大量的可持续性、合理使用和生物多样性保护。这篇综述描述了在喜马拉雅印度植物中发现的次生植物代谢产物的潜在治疗应用。该数据库包含45种用于治疗各种疾病的植物，如癌症、炎症和微生物感染。除了授权的ITIS名称外，它还包括印地语名称、科名和活性成分。关于这些分子的最重要信息可以在活性成分的超链接中找到。它包括结构（二维和三维）、名称和标识符、化学和物理性质、光谱信息、生物化学、文献和专利。该综述还引用了各种负责预防COVID-19的植物化学物质。尽管在生产天然产物方面存在一些挑战，但研究人员可以进行研究以生产出副作用少的成功药物。
