Kjaer M
Department of Neurology, Central Hospital, Holstebro, Denmark.
Electroencephalogr Clin Neurophysiol Suppl. 1987;39:291-6.
The diagnostic value of the EP tests among patients suspected of having multiple sclerosis depends on the number of silent lesions the tests reveal. This number is influenced by technique, normal material, evaluation criteria, diagnostic classification and definition of silent lesions. Although the total number of EP abnormalities is higher among patients with definite MS, the incidence of subclinical lesions found by the tests is greater in patients with an uncertain diagnosis. In such patients, VEP revealed a silent lesion in 50%, BAEP in 38%, but SEP in only 13%. An abnormal EP recording has the same diagnostic value as has an abnormal sign, so there is no need to perform an EP test if the clinical examination shows involvement of the pathways. Normal recordings may also be valuable in reassuring patients with uncharacteristic symptoms that they are probably not suffering from MS.
体感诱发电位（EP）测试在疑似患有多发性硬化症患者中的诊断价值取决于该测试所揭示的无症状性病变数量。这一数量受技术、正常材料、评估标准、诊断分类以及无症状性病变定义的影响。尽管确诊为多发性硬化症的患者中EP异常的总数更高，但测试发现的亚临床病变发生率在诊断不明确的患者中更高。在这类患者中，视觉诱发电位（VEP）显示50%存在无症状性病变，脑干听觉诱发电位（BAEP）为38%，但躯体感觉诱发电位（SEP）仅为13%。异常的EP记录与异常体征具有相同的诊断价值，因此，如果临床检查显示神经通路受累，则无需进行EP测试。正常记录对于让有非典型症状的患者放心，认为他们可能未患多发性硬化症也可能有价值。
