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Intermediate-dose cytarabine or standard-dose cytarabine plus single-dose anthracycline as post-remission therapy in older patients with acute myeloid leukemia: impact on health care resource consumption and outcomes.

作者信息

Galtier Jean, Alric Camille, Bérard Emilie, Leguay Thibaut, Tavitian Suzanne, Bidet Audrey, Delabesse Eric, Rieu Jean Baptiste, Vial Jean-Philippe, Vergez François, Lechevalier Nicolas, Luquet Isabelle, Klein Emilie, de Grande Anne-Charlotte, Sarry Audrey, Pigneux Arnaud, Récher Christian, Bertoli Sarah, Dumas Pierre-Yves

机构信息

CHU Bordeaux, Service d'Hématologie Clinique et de Thérapie Cellulaire, F-33000, Bordeaux, France.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

出版信息

Blood Cancer J. 2021 Nov 13;11(11):180. doi: 10.1038/s41408-021-00551-y.

DOI:10.1038/s41408-021-00551-y
PMID:34775463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8590686/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c199/8590686/f343b06ed08d/41408_2021_551_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c199/8590686/f343b06ed08d/41408_2021_551_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c199/8590686/f343b06ed08d/41408_2021_551_Fig1_HTML.jpg

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本文引用的文献

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Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission.口服阿扎胞苷维持治疗急性髓系白血病缓解后。
N Engl J Med. 2020 Dec 24;383(26):2526-2537. doi: 10.1056/NEJMoa2004444.
2
Post-remission therapy of adults aged 60 and older with acute myeloid leukemia in first complete remission: role of treatment intensity on the outcome.60 岁及以上初诊完全缓解的急性髓系白血病成人患者的缓解后治疗:治疗强度对结局的影响。
Ann Hematol. 2020 Apr;99(4):773-780. doi: 10.1007/s00277-020-03922-w. Epub 2020 Feb 22.
3
Improved Survival by Adding Lomustine to Conventional Chemotherapy for Elderly Patients With AML Without Unfavorable Cytogenetics: Results of the LAM-SA 2007 FILO Trial.
对于无不良细胞遗传学特征的老年急性髓系白血病患者,在传统化疗基础上加用洛莫司汀可提高生存率:LAM-SA 2007 FILO试验结果
J Clin Oncol. 2018 Nov 10;36(32):3203-3210. doi: 10.1200/JCO.2018.78.7366. Epub 2018 Sep 27.
4
Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.成人急性髓系白血病的诊断与管理:2017年国际专家小组的欧洲白血病网络(ELN)建议
Blood. 2017 Jan 26;129(4):424-447. doi: 10.1182/blood-2016-08-733196. Epub 2016 Nov 28.
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The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.2016 年版世界卫生组织髓系肿瘤和急性白血病分类。
Blood. 2016 May 19;127(20):2391-405. doi: 10.1182/blood-2016-03-643544. Epub 2016 Apr 11.
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Impact of post-remission therapy in patients aged 65-70 years with de novo acute myeloid leukemia: a comparison of two concomitant randomized ALFA trials with overlapping age inclusion criteria.65-70 岁初发急性髓系白血病患者缓解后治疗的影响:两个伴有重叠年龄纳入标准的同时随机 ALFA 试验的比较。
Haematologica. 2011 Jun;96(6):837-44. doi: 10.3324/haematol.2010.036921. Epub 2011 Apr 1.
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Randomized study of intensified anthracycline doses for induction and recombinant interleukin-2 for maintenance in patients with acute myeloid leukemia age 50 to 70 years: results of the ALFA-9801 study.50 至 70 岁急性髓系白血病患者强化蒽环类药物诱导和重组白细胞介素-2 维持治疗的随机研究:ALFA-9801 研究结果。
J Clin Oncol. 2010 Feb 10;28(5):808-14. doi: 10.1200/JCO.2009.23.2652. Epub 2010 Jan 4.
8
Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial.老年急性髓系白血病患者在强化诱导化疗后首次完全缓解期的缓解后治疗:多中心随机急性白血病法国协会(ALFA)9803试验结果
Blood. 2007 Jun 15;109(12):5129-35. doi: 10.1182/blood-2007-02-069666. Epub 2007 Mar 6.
9
Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine.老年初发急性髓系白血病患者缓解后治疗:一项比较米托蒽醌与中剂量阿糖胞苷及标准剂量阿糖胞苷的随机试验
Blood. 2001 Aug 1;98(3):548-53. doi: 10.1182/blood.v98.3.548.
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Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B.成人急性髓系白血病缓解后强化化疗。癌症与白血病B组。
N Engl J Med. 1994 Oct 6;331(14):896-903. doi: 10.1056/NEJM199410063311402.