Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Otorhinolaryngology, The First Hospital of Jilin University, Changchun, China.
Acta Otolaryngol. 2021 Dec;141(12):1049-1054. doi: 10.1080/00016489.2021.1922754. Epub 2021 Nov 13.
Decompensated tinnitus substantially degrades quality of life. Anxiety and poor sleep are comorbidities in decompensated tinnitus.
This multicenter study was designed to investigate the risk factors of decompensated tinnitus and to analyze the interaction effect of anxiety and poor sleep on decompensated tinnitus by conducting a multicenter study.
We retrospectively analyzed patients with subjective chronic tinnitus who presented to five Chinese hospitals in China from September 2019 to November 2020. Demographic characteristics, pure tone audiometry, tinnitus-related tests, psychometric and sleep questionnaires were applied.
A total of 338 patients were included, and 99 (29.3%) patients were in the decompensated group. Poor sleep and anxiety were possible risk factors of decompensated tinnitus by a forced-entry binary logistic analysis. Sleep disturbances and anxiety had an additive interaction that accounted for 87% of the decompensated tinnitus cases in our study population (RERI = 10.96, = 18.22, AP = 0.87).
Anxiety and sleep disturbances are possible risk factors of decompensated tinnitus. The combination of poor sleep and anxiety exerts a greater impact on tinnitus severity than either risk factor alone.
代偿性耳鸣会显著降低生活质量。焦虑和睡眠不佳是代偿性耳鸣的共病。
本多中心研究旨在探讨代偿性耳鸣的危险因素，并通过多中心研究分析焦虑和睡眠不佳对代偿性耳鸣的交互作用。
我们回顾性分析了 2019 年 9 月至 2020 年 11 月期间来自中国五家医院的 338 名患有主观性慢性耳鸣的患者。应用了人口统计学特征、纯音听阈测试、耳鸣相关测试、心理计量和睡眠问卷。
共纳入 338 例患者，其中 99 例（29.3%）患者为代偿性耳鸣组。通过强制进入二元逻辑分析，睡眠不佳和焦虑可能是代偿性耳鸣的危险因素。睡眠障碍和焦虑具有相加交互作用，占研究人群中代偿性耳鸣病例的 87%（RERI=10.96，=18.22，AP=0.87）。
焦虑和睡眠障碍可能是代偿性耳鸣的危险因素。睡眠不佳和焦虑的组合对耳鸣严重程度的影响大于任何单一因素。
