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保留双心室功能的 Yasui 手术的外科治疗结果:单中心经验。

Surgical outcome of Yasui procedure for preserving biventricular function: single centre experience.

机构信息

Department of Cardiac Sciences, Section of Pediatric Cardiology, King Abdulaziz Cardiac Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.

King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia.

出版信息

Cardiol Young. 2022 Oct;32(10):1570-1574. doi: 10.1017/S1047951121004546. Epub 2021 Nov 15.

Abstract

BACKGROUND

Yasui procedure is surgical repair intended to preserve biventricular function for patients with left ventricle outflow tract obstruction associated with aortic arch lesions and ventricular septal defect.

METHODS

Retrospective chart review analysis of all patients who had Yasui procedure (2008-2020) comparing midterm outcome of one versus two stage repair.

RESULTS

Twenty patients (70% female) underwent Yasui procedure in our center. Eight patients (40%) had left ventricle outflow tract obstruction /interrupted aortic arch, 7 patients (35%) had left ventricle outflow tract obstruction /coarctation of aorta, 3 patients (15%) had double outlet ventricle and ventricular septal defect that were unattainable for tunneling to one of the semilunar valves without creating obstruction, and 2 patients (10%) had aortic atresia with hypoplastic aortic arch. All patients had associated ventricular septal defect. Fifteen patients (75%) had one-stage repair and 5 patients (25%) had two-stage repair. Means age and weight for one and two-stage repair were 1.3 ± 2 months, 13.4 ± 11.5 months and 3.3 ± 0.6 kg, 7.8 ± 3.4 kg, respectively. During follow up, 8 patients (40%) required re- intervention, mainly for right ventricle-pulmonary artery conduit either dilation or replacement. The average duration of follow up was 5 years with nil mortality.

CONCLUSION

Yasui procedure is effective approach for children who have left ventricle outflow tract obstruction associated with aortic arch anomalies and ventricular septal defect. Survival rate with single or staged repair is comparably good. During the first 5 year of follow up, nearly 40% of operated patients required re-intervention.

摘要

背景

Yasui 手术是一种旨在为左心室流出道梗阻合并主动脉弓病变和室间隔缺损的患者保留双心室功能的外科修复手术。

方法

对 2008 年至 2020 年间在我中心接受 Yasui 手术的所有患者进行回顾性图表分析,比较一期和两期修复的中期结果。

结果

我中心共有 20 例(70%为女性)患者接受了 Yasui 手术。8 例(40%)患者存在左心室流出道梗阻/主动脉弓中断,7 例(35%)患者存在左心室流出道梗阻/主动脉缩窄,3 例(15%)患者存在双出口心室和室间隔缺损,这些缺损无法通过隧道到达其中一个半月瓣而不造成梗阻,2 例(10%)患者存在主动脉瓣闭锁伴主动脉弓发育不良。所有患者均存在室间隔缺损。15 例(75%)患者行一期修复,5 例(25%)患者行两期修复。一期和两期修复的平均年龄和体重分别为 1.3±2 个月、13.4±11.5 个月和 3.3±0.6kg、7.8±3.4kg。随访期间,8 例(40%)患者需要再次介入治疗,主要是右心室-肺动脉通道扩张或更换。平均随访时间为 5 年,无死亡病例。

结论

Yasui 手术是治疗左心室流出道梗阻合并主动脉弓畸形和室间隔缺损的有效方法。一期或分期修复的存活率相当好。在随访的前 5 年中,近 40%的手术患者需要再次介入治疗。

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