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半侧颌面部发育异常:两名患者中一种新发现的疾病,表现为面部不对称、面部皮肤多毛、上颌单侧增大及牙齿发育不全。

Hemimaxillofacial dysplasia: a newly recognized disorder of facial asymmetry, hypertrichosis of the facial skin, unilateral enlargement of the maxilla, and hypoplastic teeth in two patients.

作者信息

Miles D A, Lovas J L, Cohen M M

机构信息

Department of Oral Diagnosis and Oral Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.

出版信息

Oral Surg Oral Med Oral Pathol. 1987 Oct;64(4):445-8. doi: 10.1016/0030-4220(87)90150-2.

DOI:10.1016/0030-4220(87)90150-2
PMID:3477765
Abstract

Hemimaxillofacial dysplasia is a newly recognized disorder consisting of unilateral enlargement of the maxillary alveolar bone and the gingiva associated with hypoplastic teeth, facial asymmetry, and hypertrichosis of the facial skin on the ipsilateral side. The overall pattern of abnormalities in both of the patients presented in this article differs significantly from previously reported types of maxillofacial asymmetry. The occurrence of the same abnormalities in two or more unrelated patients suggests, but does not prove, that pathogenesis in both cases may be the same. The present disorder needs further delineation. At present, neither the cause nor the pathogenesis is understood.

摘要

半侧颌面部发育异常是一种新发现的疾病,其特征为上颌牙槽骨和牙龈单侧增大,并伴有牙齿发育不全、面部不对称以及同侧面部皮肤多毛症。本文所呈现的两位患者的总体异常模式与先前报道的颌面部不对称类型有显著差异。两名或更多无血缘关系的患者出现相同异常提示(但未证实)这两种情况的发病机制可能相同。目前这种疾病需要进一步明确。目前,其病因和发病机制均不明。

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