Reddemann H, Schwesinger G, Riethdorf L
Hämatologisch-Onkologische Abteilung der Klinik für Kindermedizin, Ernst-Moritz-Arndt-Universität Greifswald.
Psychiatr Neurol Med Psychol (Leipz). 1987 Jun;39(6):365-71.
Intrathecal methotrexate-overdosage in the meningosis therapy leads to CNS damages dependent on dose. It was given a own case report and a literature review with clinical symptoms and the therapy in this complication. Neuropathologic findings included demyelinisation und necrosis of the white matter.
