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脑瘫患儿斜视修复术的研究

Strabismus Repair in Children with Varying Severity of Cerebral Palsy.

机构信息

Department of Ophthalmology, Lebanese American University Medical Center, Beirut, Lebanon.

出版信息

Semin Ophthalmol. 2022 Feb 17;37(2):265-267. doi: 10.1080/08820538.2021.2003823. Epub 2021 Nov 14.

DOI:10.1080/08820538.2021.2003823
PMID:34779343
Abstract

OBJECTIVE

To study the success rate of strabismus surgery in patients with varying levels of severity of cerebral palsy (CP).

DESIGN

A retrospective study was conducted.

PARTICIPANTS

Sixty-four patients with varying severity of CP were included.

METHODS

All patients with different CP severity levels underwent strabismus surgery. Success was defined as any postoperative heterotropia outcome of less than 10 prism diopters in primary position. Statistical analysis was conducted using chi-square.

RESULTS

The mean age at the time of strabismus surgery was 3.1 years, and the mean follow-up was 6.0 years. The most common types of strabismus were infantile-onset exotropia in 36 patients (56%) and infantile-onset esotropia in 28 patients (44%). Surgical success was found to be better in patients with mild GMFCS (GMFCS levels 1-2) with 68% having less than 10 PD of eso or exotropia in primary gaze, as compared to patients with severe GMFCS (GMFCS levels 3-5) (38% with 10 PD of heterotropia) ( < .05; χ2). Refractive errors included myopia (27.5% in mild cases and 41.6% in severe), emmetropia (10% in mild and 8.3% in severe) and hyperopia (62.5% in mild and 50% in severe). Around 50% of the mild cases had absent binocular fusion compared to 66.6% of those with severe CP. Amblyopia was found in 62.5% of the mild cases and 54.1% of the severe cases. Nystagmus was present in 25% with mild disease and 29.1% of those with severe disease.

CONCLUSION

Restoration of good ocular alignment in patients with CP is achievable in more than half of the cases. Patients with more severe CP have poorer outcomes than those with milder palsies. There appears to be no difference in outcomes between the different types of strabismus.

摘要

目的

研究不同脑瘫(CP)严重程度患者斜视手术的成功率。

设计

回顾性研究。

参与者

共纳入 64 例不同 CP 严重程度的患者。

方法

所有 CP 严重程度不同的患者均接受斜视手术。术后斜视度小于 10 棱镜屈光度为正位视为手术成功。采用卡方检验进行统计学分析。

结果

斜视手术时的平均年龄为 3.1 岁,平均随访时间为 6.0 年。最常见的斜视类型为 36 例(56%)的婴儿期起始性外斜视和 28 例(44%)的婴儿期起始性内斜视。与严重 CP 患者(GMFCS 3-5 级,斜视度 10 PD 者占 38%)相比,GMFCS 1-2 级(斜视度 10 PD 者占 68%)的轻度 CP 患者手术成功率更高(<.05;χ2)。屈光不正包括近视(轻度 27.5%,重度 41.6%)、正视(轻度 10%,重度 8.3%)和远视(轻度 62.5%,重度 50%)。轻度病例中约 50%的患者无双眼融合,而重度 CP 患者中则有 66.6%的患者无双眼融合。轻度病例中有 62.5%的患者存在弱视,重度病例中有 54.1%的患者存在弱视。轻度疾病患者中有 25%存在眼球震颤,重度疾病患者中有 29.1%存在眼球震颤。

结论

CP 患者中,超过一半的患者可以获得良好的眼位矫正。CP 较严重的患者手术效果较 CP 轻者差。不同类型斜视的手术效果似乎没有差异。

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Prevalence and types of strabismus in cerebral palsy: A global and historical perspective based on a systematic review and meta-analysis.脑瘫患者斜视的患病率及类型:基于系统评价和荟萃分析的全球及历史视角
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