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发生于下颌下间隙的梭形细胞脂肪瘤:第五例报告并结合文献复习。

Spindle Cell Lipoma Occurring in the Submandibular Space: Fifth Case Reported along with a Concise Review of the Literature.

机构信息

Dept. of Oral Pathology and Microbiology & Forensic odontology. Laxmi bai institute of dental sciences and hospital, Patiala, Punjab, India.

Waryam Singh Hospital, Yamunanagar, Haryana, India.

出版信息

Acta Medica (Hradec Kralove). 2021;64(3):174-182. doi: 10.14712/18059694.2021.30.

DOI:10.14712/18059694.2021.30
PMID:34779384
Abstract

Spindle cell lipoma (SCL) is an uncommon histological variant of lipoma that accounts for 1.5% of all adipose tumors. It rarely occurs in the oral cavity. The most common sites of involvement are the buccal mucosa, tongue, lip, alveolar mucosa, gingiva, and palate. Submandibular space is a very rare site of occurrence for SCL. When occurs in this site, SCL mainly involves the 4th-7th decade with a female predominance. Due to wide communications of submandibular space, the actual extent and appearance of the lesions present here gets masked up especially those involving the deeper tissues leading to an inaccurate diagnosis. Wide overlap of clinical and histopathological features of SCL to other clinical pathologies leads to a challenging task for the clinicians to reach an accurate diagnosis. To our knowledge, only four cases of intraoral SCL involving the submandibular region directly or indirectly have been reported in the literature. Here we represent another rare case of SCL in an 18-year-old male patient along with a concise review of the literature. This case appears to be quite rare due to its location (submandibular space), age, and sex of the patient (18/M).

摘要

梭形细胞脂肪瘤(SCL)是一种罕见的脂肪瘤组织学变异型,占所有脂肪肿瘤的 1.5%。它很少发生在口腔内。最常见的受累部位是颊黏膜、舌、唇、牙槽黏膜、牙龈和 palate。下颌下间隙是 SCL 非常罕见的发生部位。当发生在下颌下间隙时,SCL 主要发生在 40-70 岁,女性居多。由于下颌下间隙广泛相通,此处病变的实际范围和外观被掩盖,尤其是那些涉及深部组织的病变,导致诊断不准确。SCL 的临床和组织病理学特征与其他临床病理学广泛重叠,给临床医生准确诊断带来挑战。据我们所知,文献中仅报道了 4 例直接或间接累及下颌下区的口腔内 SCL。在此,我们报告了另一个罕见的下颌下间隙 SCL 病例,并对文献进行了简要回顾。由于该病例的位置(下颌下间隙)、患者的年龄和性别(18 岁男性),该病例似乎非常罕见。

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Spindle Cell Lipoma Occurring in the Submandibular Space: Fifth Case Reported along with a Concise Review of the Literature.发生于下颌下间隙的梭形细胞脂肪瘤:第五例报告并结合文献复习。
Acta Medica (Hradec Kralove). 2021;64(3):174-182. doi: 10.14712/18059694.2021.30.
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