State Key Laboratory of Biobased Material and Green Papermaking, School of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan, 250353, China.
College of Science, Huzhou University, Huzhou, Zhejiang, 313000, China.
Anal Methods. 2021 Dec 2;13(46):5628-5637. doi: 10.1039/d1ay01357b.
In this work, Ni-Cu bimetallic alloy nanoparticles supported on reduced graphene oxide (Ni-Cu ANPs/RGO) was successfully fabricated through a one-step hydrothermal synthesis method, where simultaneous reduction of graphene oxide, nickel salt and copper salt was performed, and relevant characterization studies were executed. This synthetic method does not require surfactants and high temperature treatment, and is recommended as a green, convenient and effective way to produce composites. The unique two-dimensional architecture of the RGO provides a large specific surface area, contributing to loading more Ni-Cu ANPs, while the uniformly distributed Ni-Cu bimetallic alloy nanoparticles enhance the electrocatalytic performance of glucose oxidation. The non-enzymatic glucose biosensor based on Ni-Cu ANPs/RGO showed a wide linear range (from 0.01 μM to 30 μM), low detection limit (0.005 μM), and excellent sensitivity (1754.72 μA mM cm). More importantly, the high reliability and the excellent selectivity in actual sample detection will broaden its practical application in electrochemical sensing.
在这项工作中，通过一步水热合成方法成功制备了负载在还原氧化石墨烯（Ni-Cu ANPs/RGO）上的镍-铜双金属合金纳米粒子，其中同时进行了氧化石墨烯、镍盐和铜盐的还原，并且进行了相关的表征研究。这种合成方法不需要表面活性剂和高温处理，被推荐为生产复合材料的一种绿色、方便和有效的方法。RGO 的独特二维结构提供了较大的比表面积，有利于负载更多的 Ni-Cu ANPs，而均匀分布的 Ni-Cu 双金属合金纳米粒子增强了葡萄糖氧化的电催化性能。基于 Ni-Cu ANPs/RGO 的非酶葡萄糖生物传感器具有较宽的线性范围（从 0.01 μM 到 30 μM）、较低的检测限（0.005 μM）和优异的灵敏度（1754.72 μA mM cm）。更重要的是，在实际样品检测中具有较高的可靠性和出色的选择性，将拓宽其在电化学传感中的实际应用。
