King Fahad Medical City, Riyadh Saudi Arabia.
King Fahad Medical City, Riyadh Saudi Arabia.
Photodiagnosis Photodyn Ther. 2022 Mar;37:102625. doi: 10.1016/j.pdpdt.2021.102625. Epub 2021 Nov 12.
To assess the influence of different photosensitizers activated by PDT as a disinfectant in comparison to conventional sodium hypochlorite (NaOCl) on the EBS (extrusion bond strength) of FRCP with radicular dentin.
A total of fifty single-rooted human maxillary central incisors with fully developed apices were selected. Endodontic treatment of samples was performed using 10 K file to obtain patency than sequentially with a 25 K file followed by rotary pro tapers till F2 with constant irrigation. The canal was dried and obturated with corresponding gutta-percha and sealer. A Peso reamer was employed to prepare post space. Based on canal disinfection regimes, samples were divided into five groups. Group 1 Riboflavin (RF)+17%EDTA, group 2 Rose bengal (RB) +17%EDTA, group 3 Curcumin CP +17%EDTA, group 4 Porfimer sodium, Photofrin (PS) +17%EDTA and group 5 2.25% NaOCl +17% EDTA (control). Following disinfection, the canal space of all specimens was dried followed by FRCP cementation. Specimens were placed on a Universal testing machine (UTM) for EBS. The type of bond failure was evaluated using a stereomicroscope. ANOVA and Tukey multiple comparison tests were used to compare means.
The highest EBS was shown by group 1 canal disinfected with riboflavin (RF) and 17% EDTA at all three levels. The lowest EBS was displayed in group 5 canal cleaned with 2.25% NaOCl and 17% EDTA. Intragroup assessment disclosed a decrease in EBS from cervical one-third to apical one-third in all experimental groups. Intergroup comparison revealed group 4 using PS and 17% EDTA and group 5 canal disinfected with 2.25% NaOCl and 17% EDTA at all three levels of root structure coronal, middle, and apical exhibited comparable EBS (p>0.05).
Root canal dentin treated with different PS (RF, RB, CP) has the potential to be used as canal disinfection as it demonstrates better EBS than the conventional disinfecting regime (2.25% NaOCl +17% EDTA). PS and 17% EDTA as a canal disinfectant need further investigation.
评估 PDT 激活的不同光敏剂作为消毒剂与传统次氯酸钠 (NaOCl) 相比对根管牙本质的 FRCP（挤出结合强度）的影响。
选择 50 颗完全发育的上颌中切牙。采用 10 K 文件对样本进行根管治疗，以获得通畅性，然后依次用 25 K 文件进行治疗，然后用旋转 ProTapers 直至 F2，同时保持持续冲洗。用相应的牙胶和密封剂填充根管。采用 Peso 扩孔器制备桩腔。根据根管消毒方案，将样本分为五组。第 1 组为核黄素 (RF)+17%EDTA，第 2 组为孟加拉玫瑰红 (RB)+17%EDTA，第 3 组为姜黄素 CP+17%EDTA，第 4 组为卟啉钠、血卟啉 (PS)+17%EDTA，第 5 组为 2.25%NaOCl+17%EDTA（对照组）。消毒后，所有样本的根管空间均干燥，然后进行 FRCP 粘固。将样本置于万能试验机 (UTM) 上进行 EBS 测试。使用立体显微镜评估粘结失败的类型。采用方差分析和 Tukey 多重比较检验比较均值。
用核黄素 (RF) 和 17%EDTA 消毒的第 1 组根管显示出最高的 EBS。用 2.25%NaOCl 和 17%EDTA 消毒的第 5 组根管显示出最低的 EBS。组内评估显示，所有实验组的 EBS 从颈三分之一下降到根尖三分之一。组间比较显示，使用 PS 和 17%EDTA 的第 4 组和用 2.25%NaOCl 和 17%EDTA 消毒的第 5 组在根管结构的冠、中、根尖三个水平的 EBS 相似（p>0.05）。
用不同 PS（RF、RB、CP）处理根管牙本质有作为根管消毒的潜力，因为它显示出比传统消毒方案（2.25%NaOCl+17%EDTA）更好的 EBS。PS 和 17%EDTA 作为根管消毒剂需要进一步研究。
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