Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education (MAHE), Manipal, India.
Department of Respiratory Medicine, Kasturba Medical College, MAHE, Manipal, India.
Syst Rev. 2021 Nov 15;10(1):297. doi: 10.1186/s13643-021-01853-9.
Idiopathic pulmonary fibrosis (IPF) is one of the common types of interstitial lung disease having high prevalence and mortality worldwide. As a result of patient-centred hindering factors of adherence to centre-based pulmonary rehabilitation (PR), home-based PR is an alternate mode of rehabilitating individuals with IPF. This systematic review will evaluate the effectiveness of unsupervised home-based PR on functional capacity and health-related quality of life (HRQoL) in individuals with IPF.
Clinically stable, high resolution computed tomography and physician diagnosed IPF participants having modified Medical Research Council score below 5 will be considered for the systematic review. Studies involving home-based PR as an intervention to treat individuals with IPF will be considered. Randomised controlled trials and quasi-randomised studies (with two groups followed up) are eligible to be included. Outcomes of our interest are functional capacity (6-min walk distance, shuttle walk test and incremental shuttle walk test) and secondary outcome measure would include assessment of quality of life and adverse effects of intervention. Electronic databases such as SCOPUS, Medline (PubMed and Web of Science), PEDRo and CINAHL will be searched using database specific terms. Additionally, forward and backward citations of included studies will be searched to identify potential records. Two review authors, independently, will conduct the screening, data extraction using a customised standard tool, and critical appraisal using Cochrane Risk of Bias 2 tool of included studies. If data permits, meta-analysis will be conducted. In case of substantial heterogeneity, we will do a narrative synthesis. Subgroup analysis will be undertaken based on various contextual and interventional factors.
This review will provide comprehensive evidence on the effectiveness of unsupervised home-based PR to physiotherapists, policy makers and researchers who are interested in IPF management. Findings from this review may guide the development and evaluation of more robust evidence based home-based PR that aimed to improve functional capacity among people with IPF.
PROSPERO CRD42020213883.
特发性肺纤维化（IPF）是一种常见的间质性肺疾病类型，在全球范围内具有较高的患病率和死亡率。由于以患者为中心的坚持参与中心为基础的肺康复（PR）的阻碍因素，家庭为基础的 PR 是一种替代模式，可用于康复 IPF 患者。本系统评价将评估非监督家庭为基础的 PR 在功能能力和与健康相关的生活质量（HRQoL）方面对 IPF 患者的有效性。
将考虑具有以下特征的临床稳定、高分辨率计算机断层扫描和医生诊断为 IPF 的参与者进行系统评价：改良医学研究委员会评分低于 5 分，且有能力进行家庭为基础的 PR。将考虑将家庭为基础的 PR 作为治疗 IPF 患者的干预措施的研究。随机对照试验和准随机研究（两组均进行随访）有资格被纳入。我们感兴趣的结果是功能能力（6 分钟步行距离、穿梭步行试验和递增穿梭步行试验），次要结果将包括生活质量评估和干预的不良反应。将使用数据库特定术语搜索电子数据库，如 SCOPUS、Medline（PubMed 和 Web of Science）、PEDRo 和 CINAHL。此外，还将搜索纳入研究的前向和后向引文，以确定潜在的记录。两名审查作者将独立进行筛选、使用定制标准工具进行数据提取，并使用 Cochrane 偏倚风险 2 工具对纳入研究进行批判性评价。如果数据允许，将进行荟萃分析。如果存在显著异质性，将进行叙述性综合。将根据各种背景和干预因素进行亚组分析。
本综述将为对 IPF 管理感兴趣的物理治疗师、政策制定者和研究人员提供关于非监督家庭为基础的 PR 有效性的全面证据。本综述的结果可能为开发和评估旨在提高 IPF 患者功能能力的更强大的基于证据的家庭为基础的 PR 提供指导。
PROSPERO CRD42020213883。
