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Am J Kidney Dis. 2021 Oct;78(4):511-519.e1. doi: 10.1053/j.ajkd.2021.03.017. Epub 2021 May 1.
2
Real-World Experience with Coformulated Ledipasvir and Sofosbuvir for HIV-Positive Patients with HCV Genotype 2 Infection: A Multicenter, Retrospective Study.来迪派韦与索磷布韦复方制剂用于HIV阳性合并丙型肝炎病毒2型感染患者的真实世界经验:一项多中心回顾性研究
Infect Dis Ther. 2021 Jun;10(2):827-838. doi: 10.1007/s40121-021-00424-8. Epub 2021 Mar 18.
3
Microelimination of Chronic Hepatitis C by Universal Screening Plus Direct-Acting Antivirals for Incarcerated Persons in Taiwan.台湾通过对在押人员进行普遍筛查加直接抗病毒药物实现慢性丙型肝炎的微观消除
Open Forum Infect Dis. 2020 Jul 17;7(8):ofaa301. doi: 10.1093/ofid/ofaa301. eCollection 2020 Aug.
4
Taiwan is on track of accelerating hepatitis C elimination by 2025.台湾正朝着在2025年前加速消除丙型肝炎的目标迈进。
Liver Int. 2020 Jun;40(6):1506-1507. doi: 10.1111/liv.14412. Epub 2020 Mar 8.
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Global timing of hepatitis C virus elimination in high-income countries.高收入国家丙型肝炎病毒消除的全球时间表。
Liver Int. 2020 Mar;40(3):522-529. doi: 10.1111/liv.14324. Epub 2019 Dec 23.
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Effectiveness and safety of sofosbuvir/velpatasvir/voxilaprevir in patients with chronic hepatitis C previously treated with DAAs.索磷布韦/维帕他韦/伏西瑞韦治疗既往接受过 DAA 治疗的慢性丙型肝炎患者的有效性和安全性。
J Hepatol. 2019 Oct;71(4):666-672. doi: 10.1016/j.jhep.2019.06.002. Epub 2019 Jun 14.
7
Taiwan commits to eliminating hepatitis C in 2025.台湾致力于在2025年消除丙型肝炎。
Lancet Infect Dis. 2019 May;19(5):466-467. doi: 10.1016/S1473-3099(19)30170-7.
8
Achieving hepatitis C elimination in Taiwan-Overcoming barriers by setting feasible strategies.在台湾实现丙型肝炎消除——通过制定可行策略克服障碍。
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Real-world anti-viral treatment decisions among chronic hepatitis C patients in Taiwan: The INITIATE study.台湾慢性丙型肝炎患者的真实世界抗病毒治疗决策:INITIATE 研究。
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The Micro-Elimination Approach to Eliminating Hepatitis C: Strategic and Operational Considerations.微消除法治疗丙型肝炎:战略与操作考量。
Semin Liver Dis. 2018 Aug;38(3):181-192. doi: 10.1055/s-0038-1666841. Epub 2018 Jul 9.

台湾加快消除丙型肝炎的努力。

Taiwan accelerates its efforts to eliminate hepatitis C.

作者信息

Chien Rong-Nan, Lu Sheng-Nan, Pwu Raoh-Fang, Wu Grace Hui-Min, Yang Wen-Wen, Liu Chia-Ling

机构信息

Taiwan National Hepatitis C Program Office, Ministry of Health and Welfare, Taipei, Taiwan.

Liver Research Unit, Linkou Chang Gung Memorial Hospital and University, Taoyuan, Taiwan.

出版信息

Glob Health Med. 2021 Oct 31;3(5):293-300. doi: 10.35772/ghm.2021.01064.

DOI:10.35772/ghm.2021.01064
PMID:34782872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8562095/
Abstract

The estimated prevalence of anti-HCV was 3.3% (1.8-5.5%) in the general population in Taiwan with several regional disparities. The reactive anti-HCV in different regions may vary between 0% and 65%. The National Hepatitis C Program (NHCP) office estimated approximately 623,323 persons reactive with anti-HCV based on several extensive region- and cohort-wide studies. Taiwan has accelerated its efforts to eliminate hepatitis C since 2018 by committing to achieve World Health Organization (WHO)'s 2030 goal of treating 80% of eligible patients by 2025. Many aggressive measures by the Ministry of Health and Welfare (MOHW) have been ongoing including several key success factors such as political commitment by the MOHW to finance this national program and improve National Health Insurance (NHI) reimbursement restrictions for treatment. Meanwhile, the Taiwan Centers for Disease Control (CDC) instituted harm reduction programs and the Health Promotion Administration (HPA) started to improve awareness and perform national screening programs. The NHCP office instituted monitoring, evaluation, micro-elimination and funding to linkage to care programs. In addition to sustainable financing, it is imperative to scale-up screening coverage through a precision public health approach to fill the gap of under-diagnosis. Hopefully, we can achieve early elimination by announcing the treatment target of 250000 CHC patients by 2025.

摘要

台湾普通人群中抗丙型肝炎病毒(anti-HCV)的估计流行率为3.3%(1.8 - 5.5%),存在若干地区差异。不同地区抗-HCV反应性可能在0%至65%之间变化。根据多项广泛的地区和队列研究,国家丙型肝炎防治计划(NHCP)办公室估计约有623,323人抗-HCV呈反应性。自2018年以来,台湾加快了消除丙型肝炎的努力,致力于实现世界卫生组织(WHO)到2025年治疗80%符合条件患者的2030年目标。卫生福利部(MOHW)采取了许多积极措施,包括一些关键成功因素,如MOHW在财政上支持这一国家计划,并放宽国民健康保险(NHI)对治疗的报销限制。与此同时,台湾疾病管制中心(CDC)制定了减少危害计划,健康促进署(HPA)开始提高认识并开展全国筛查计划。NHCP办公室制定了监测、评估、微观消除以及与护理计划挂钩的资金安排。除了可持续融资外,必须通过精准公共卫生方法扩大筛查覆盖范围,以填补诊断不足的差距。希望我们通过宣布到2025年治疗250000例慢性丙型肝炎患者的目标能够实现早期消除。