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智力表现的早期表现:遗传对后期学业测试表现的影响是通过幼儿期的言语表现来介导的证据。

Early manifestations of intellectual performance: Evidence that genetic effects on later academic test performance are mediated through verbal performance in early childhood.

机构信息

Research Department of Clinical, Educational and Health Psychology, UCL, London, UK.

Department of Psychological Sciences, Birkbeck, University of London, London, UK.

出版信息

Child Dev. 2022 Mar;93(2):e188-e206. doi: 10.1111/cdev.13706. Epub 2021 Nov 16.

DOI:10.1111/cdev.13706
PMID:34783370
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10861934/
Abstract

Intellectual performance is highly heritable and robustly predicts lifelong health and success but the earliest manifestations of genetic effects on this asset are not well understood. This study examined whether early executive function (EF) or verbal performance mediate genetic influences on subsequent intellectual performance, in 561 U.S.-based adoptees (57% male) and their birth and adoptive parents (70% and 92% White, 13% and 4% African American, 7% and 2% Latinx, respectively), administered measures in 2003-2017. Genetic influences on children's academic performance at 7 years were mediated by verbal performance at 4.5 years (β = .22, 95% CI [0.08, 0.35], p = .002) and not via EF, indicating that verbal performance is an early manifestation of genetic propensity for intellectual performance.

摘要

智力表现具有高度遗传性,并且可以很好地预测终身健康和成功,但遗传对这一能力的早期影响尚不清楚。本研究通过对 561 名美国被领养者(57%为男性)及其亲生父母和养父母(分别有 70%、92%、13%、4%为白人,7%、2%为拉丁裔,4%为非裔美国人)进行的 2003-2017 年调查,检验了早期执行功能(EF)或语言表现是否会影响遗传对后续智力表现的影响。研究发现,4.5 岁时的语言表现可以预测孩子 7 岁时的学业表现(β=0.22,95%置信区间[0.08,0.35],p=0.002),而不是通过 EF 来预测,这表明语言表现是遗传倾向智力表现的早期表现。

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Dev Psychol. 2021 Mar;57(3):347-360. doi: 10.1037/dev0000972. Epub 2021 Feb 11.
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The Earliest Origins of Genetic Nurture: The Prenatal Environment Mediates the Association Between Maternal Genetics and Child Development.遗传与培育的最早起源:产前环境对母婴遗传与儿童发育之间的关系具有中介作用。
Psychol Sci. 2020 Jul;31(7):781-791. doi: 10.1177/0956797620917209. Epub 2020 Jun 2.
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Separating Measured Genetic and Environmental Effects: Evidence Linking Parental Genotype and Adopted Child Outcomes.分离测量的基因和环境效应:将父母基因型与领养儿童结局联系起来的证据。
Behav Genet. 2020 Sep;50(5):301-309. doi: 10.1007/s10519-020-10000-4. Epub 2020 Apr 30.
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The intergenerational transmission of mathematics achievement in middle childhood: A prospective adoption design.儿童中期数学成就的代际传递:一项前瞻性收养设计。
Dev Sci. 2020 Nov;23(6):e12974. doi: 10.1111/desc.12974. Epub 2020 May 5.
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Comparison of Adopted and Nonadopted Individuals Reveals Gene-Environment Interplay for Education in the UK Biobank.采用与未采用个体的比较揭示了英国生物库中教育的基因-环境相互作用。
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