评价选择性去腐治疗联合抗菌光动力疗法用于乳磨牙复合树脂修复的效果：一项随机对照临床试验。

Evaluation of composite restorations in primary molars subjected to selective caries removal associated with antimicrobial photodynamic therapy: A randomized controlled trial.

机构信息

Postgraduate Program in Dentistry of Niterói, Faculty of Dentistry, Federal Fluminense University, Niterói, Brazil.

Department of Specific Formation, Health Institute of Nova Friburgo, School of Dentistry, Fluminense Federal University, Nova Friburgo, Brazil.

出版信息

Int J Paediatr Dent. 2022 Jul;32(4):585-597. doi: 10.1111/ipd.12937. Epub 2022 Mar 4.

DOI:10.1111/ipd.12937

PMID:34783404

Abstract

BACKGROUND

Antimicrobial photodynamic therapy (aPDT) has been used as an adjunct treatment of deep caries lesions; however, studies on the effects of aPDT on the longevity of restorations are still limited.

AIM

To evaluate the clinical performance of composite restorations in primary molars subjected to selective caries removal (SCR) associated with aPDT.

DESIGN

A randomized clinical trial was designed. Primary molars of patients (mean age 6.15 years) with deep caries lesions without signs and symptoms of pulpal involvement were selected. A total of 64 teeth were randomly divided into groups G1 (SCR, 32 teeth) and G2 (SCR + aPDT, 32 teeth) for treatment, restored with composite, and evaluated after a week (T ), 6 months (T ), and 12 months (T ) according to the criteria of FDI. Groups were compared using the Rao-Scott chi-squared test and the logistic regression analysis for complex designs to account for multiple observations per subject (alpha = 0.05).

RESULTS

From all FDI criteria evaluated, the marginal adaptation for the SCR + aPDT group was significantly better in comparison with the SCR group at T0 and T2 in the logistic regression analysis (T0: OR = 0.151; 95% CI = 0.03-0.068, P = .015; and T2: OR = 0.201; 95% CI = 0.05-0.79, P = .022).

CONCLUSION

The marginal adaptation of primary molar resin restorations was positively affected by aPDT after 12 months of follow-up.

摘要

背景

抗菌光动力疗法（aPDT）已被用作深龋病的辅助治疗方法；然而，关于 aPDT 对修复体耐久性影响的研究仍然有限。

目的

评估选择性龋去腐（SCR）联合 aPDT 治疗乳牙深龋病的复合树脂修复体的临床效果。

设计

设计了一项随机临床试验。选择无牙髓受累症状和体征的深龋病患者（平均年龄 6.15 岁）的乳牙。共 64 颗牙齿随机分为 G1 组（SCR，32 颗牙齿）和 G2 组（SCR+aPDT，32 颗牙齿）进行治疗，用复合树脂修复，并根据 FDI 标准在治疗后一周（T ）、6 个月（T ）和 12 个月（T ）进行评估。使用 Rao-Scott 卡方检验和复杂设计的逻辑回归分析比较各组，以考虑每个受试者的多个观察结果（α=0.05）。