Department of Psychology, University of Miami, Miami, FL, USA.
AIDS Care. 2022 Oct;34(10):1219-1228. doi: 10.1080/09540121.2021.2001415. Epub 2021 Nov 16.
Substance use may predict lower rates of antiretroviral therapy (ART) adherence and viral suppression among Black Women Living with HIV (BWLWH). We assessed how perceived social support (PSS) moderates the relationship between substance use disorder (SUD) and viral load (VL) and ART adherence. 119 BWLWH provided information on PSS, SUD, alcohol use disorder (AUD) and adherence (via Wisepill). Higher PSS from friends ( = -.263, = .008) and significant others ( = -.219, = .025) predicted lower VL. SUD predicted low Wisepill adherence (a) in the past week ( = -.273, = .035) and past two weeks ( = -.273, = .033) only for women low in PSS from friends, and (b) in the past two weeks only for women low in total PSS ( = -.294, = .024). Ironically, for women high in total PSS, SUD predicted higher adherence in the past four weeks ( = .360, = .006). Adherence and VL may be bolstered by understanding the role of various forms of PSS and SUDs.
物质使用可能预示着黑人女性艾滋病毒感染者（BWLWH）接受抗逆转录病毒治疗（ART）的比例较低，病毒抑制率也较低。我们评估了感知社会支持（PSS）如何调节物质使用障碍（SUD）与病毒载量（VL）和 ART 依从性之间的关系。119 名 BWLWH 提供了有关 PSS、SUD、酒精使用障碍（AUD）和依从性（通过 Wisepill）的信息。来自朋友的更高 PSS（ = −.263， = .008）和重要他人（ = −.219， = .025）预测 VL 较低。SUD 预测过去一周（ = −.273， = .035）和过去两周（ = −.273， = .033）的 Wisepill 依从性低，仅适用于来自朋友的 PSS 低的女性，以及（b）仅适用于总 PSS 低的女性（ = −.294， = .024）。具有讽刺意味的是，对于总 PSS 较高的女性，SUD 预测过去四周的依从性较高（ = .360， = .006）。通过了解各种形式的 PSS 和 SUD 的作用，可能会增强对依从性和 VL 的理解。
MMWR Morb Mortal Wkly Rep. 2019-5-10
AIDS Patient Care STDS. 2019-4
Community Ment Health J. 2018-11
J Gen Intern Med. 2016-9
Zotero 插件