Jeon Ga Won, Choo Hye Jung, Kwon Yong Uk
Department of Pediatrics, Inha University Hospital, Inha University College of Medicine, Incheon, Korea.
Department of Radiology, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Clin Exp Pediatr. 2022 May;65(5):262-268. doi: 10.3345/cep.2021.01074. Epub 2021 Nov 5.
The delayed diagnosis of developmental dysplasia of the hip (DDH) requires complex treatment and sometimes progresses to hip osteoarthritis.
This study aimed to evaluate the risk factors and screening time for DDH in preterm infants.
A total of 155 preterm infants with a gestational age <32 weeks screened for DDH with ultrasonography were enrolled in this retrospective chart review.
The incidence of DDH was 6.45% (10 of 155). Gestational age, birth weight, sex ratio, and breech presentation did not differ significantly between infants treated for DDH (n=10) and nontreated infants (n=145) (gestational age, 29.2±1.4 weeks vs. 29.6±2.0 weeks, P=0.583; birth weight, 1,240±237 g vs. 1,295±335 g, P=0.607; female sex, 7 of 10 (70.0%) vs. 77 of 145 (53.1%), P=0.346; and breech presentation, 5 of 10 (50.0%) vs. 43 of 145 (29.7%), P=0.286, respectively). Performing the first ultrasonography earlier than 38 weeks of postmenstrual age (PMA) increased the risk of an abnormal finding by 3.76 times compared to performing it at ≥38 weeks of PMA. These abnormal findings on ultrasonography resolved spontaneously. Breech presentation increased the risk of minor abnormal findings on the first ultrasonography by 3.11 times versus nonbreech presentation and resolved spontaneously. DDH in preterm infants did not occur predominantly on the left side or in infants born with breech presentation.
Performing ultrasonography screening earlier than 38 weeks of PMA caused unnecessary subsequent ultrasonography and overtreatment. Breech presentation was not a risk factor for DDH in preterm infants. However, breech presentation could increase the risk of minor abnormal findings at the 1st ultrasonography compared to nonbreech presentation, which resolved spontaneously. The etiology and risk factors for DDH in preterm infants are somewhat different from those for DDH in term infants.
发育性髋关节发育不良(DDH)的延迟诊断需要复杂的治疗,且有时会进展为髋骨关节炎。
本研究旨在评估早产儿DDH的危险因素及筛查时间。
本回顾性病历研究纳入了155例胎龄<32周且接受超声检查筛查DDH的早产儿。
DDH的发生率为6.45%(155例中有10例)。接受DDH治疗的婴儿(n = 10)与未接受治疗的婴儿(n = 145)在胎龄、出生体重、性别比和臀位方面无显著差异(胎龄:29.2±1.4周 vs. 29.6±2.0周,P = 0.583;出生体重:1240±237 g vs. 1295±335 g,P = 0.607;女性:10例中有7例(70.0%) vs. 145例中有77例(53.1%),P = 0.346;臀位:10例中有5例(50.0%) vs. 145例中有43例(29.7%),P = 0.286)。与在孕龄(PMA)≥38周时进行首次超声检查相比,在PMA<38周时进行首次超声检查使发现异常的风险增加了3.76倍。这些超声检查的异常发现可自发缓解。与非臀位相比,臀位使首次超声检查出现轻微异常发现的风险增加了3.11倍,且可自发缓解。早产儿的DDH并非主要发生在左侧或臀位出生的婴儿中。
在PMA<38周时进行超声检查筛查会导致不必要的后续超声检查及过度治疗。臀位不是早产儿DDH的危险因素。然而,与非臀位相比,臀位可能会增加首次超声检查出现轻微异常发现的风险,且这些异常发现可自发缓解。早产儿DDH的病因和危险因素与足月儿的DDH有所不同。