双节段颈椎间盘切除融合术与混合式全椎间盘置换术治疗双节段颈椎神经根病/脊髓病的比较研究:一项针对印度人群的至少2年随访的比较研究。
Two-Level Anterior Cervical Discectomy and Fusion versus Hybrid Total Disc Replacement for Bilevel Pathology with Cervical Radiculopathy/Myelopathy: A Comparative Study with a Minimum 2-Year Follow-up in an Indian Population.
作者信息
Sharma Jeevan Kumar, Varma Kalidindi Kalyan Kumar, Mallepally Abhinandan Reddy, Marathe Nandan, Rustagi Tarush, Mohapatra Bibhudendu, Yadav Padmini, Das Kalidutta
机构信息
Indian Spinal Injuries Center, New Delhi, India.
Department of Plastic Surgery, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Asian Spine J. 2022 Aug;16(4):493-501. doi: 10.31616/asj.2021.0209. Epub 2021 Nov 18.
STUDY DESIGN
Retrospective study.
PURPOSE
To study the outcomes of two-level anterior cervical discectomy and fusion (2L-ACDF) versus hybrid total disc replacement (H-TDR) for cervical myeloradiculopathy.
OVERVIEW OF LITERATURE
For bilevel disc issues of the cervical spine, 2L-ACDF has been a historical tool with numerous implants used at different time frames. Recent developments in total disc replacement at mobile level with fusion at a spondylotic level known as hybrid fixation have added a new armamentarium for such disorders.
METHODS
An analysis of 49 consecutive patients who underwent 2L-ACDF (n=22) and H-TDR (n=27) from January 1, 2014 to December 31, 2017 was performed. Data were studied as retrieved from InstaPACS ver. 4.0 (Mediff Technologies Pvt. Ltd., Bengaluru, India) and medical records.
RESULTS
Twenty-two patients with 2L-ACDF and 27 patients with H-TDR were included. The mean±standard deviation (SD) follow-up duration was 4.0±1.5 years in H-TDR and 3.1±1.1 years in 2L-ACDF. The mean±SD Neck Disability Index (NDI) decreased from 26.1±7.6 to 6.5±3.9 in the H-TDR group and from 27.6±7.2 to 6.4±4.8 in the 2L-ACDF group at final follow-up. Disc height at suprajacent level in the 2L-ACDF group was 4.12±0.48 mm, 4.10±0.45 mm, and 4.05±0.48 mm preoperatively, at 1-year, and final follow-up, respectively. Disc height at supradjacent level in the H-TDR group was 4.28±0.36 mm, 4.20±0.32 mm, and 4.19±0.34 mm preoperatively, at 1-year, and final follow-up, respectively.
CONCLUSIONS
There was significantly improved NDI in both groups. Adjacent segment disc height loss was greater in the 2L-ACDF group than in H-TDR but not statistically significant (p =0.304). Supradjacent segment range of motion was greater in the 2L-ACDF group than in the H-TDR group (p =0.003). Both findings supported radiographic adjacent segment degeneration (ASD), but symptomatic ASD was absent in both groups.
研究设计
回顾性研究。
目的
研究双节段颈椎前路椎间盘切除融合术(2L - ACDF)与混合式全椎间盘置换术(H - TDR)治疗颈椎脊髓神经根病的疗效。
文献综述
对于颈椎的双节段椎间盘问题,2L - ACDF一直是一种历史悠久的治疗手段,在不同时期使用了多种植入物。近年来,在活动节段进行全椎间盘置换并在退变节段进行融合的所谓混合固定技术的发展,为这类疾病增添了新的治疗方法。
方法
对2014年1月1日至2017年12月31日期间连续接受2L - ACDF(n = 22)和H - TDR(n = 27)治疗的49例患者进行分析。数据来自InstaPACS ver. 4.0(印度班加罗尔Mediff Technologies Pvt. Ltd.)和病历记录。
结果
纳入22例行2L - ACDF的患者和27例行H - TDR的患者。H - TDR组的平均±标准差(SD)随访时间为4.0±1.5年,2L - ACDF组为3.1±1.1年。最终随访时,H - TDR组的平均±SD颈部功能障碍指数(NDI)从26.1±7.6降至6.5±3.9,2L - ACDF组从27.6±7.2降至6.4±4.8。2L - ACDF组相邻节段术前、术后1年和最终随访时的椎间盘高度分别为4.12±0.48 mm、4.10±0.45 mm和4.05±0.48 mm。H - TDR组相邻节段术前、术后1年和最终随访时的椎间盘高度分别为4.28±0.36 mm、4.20±0.32 mm和4.19±0.34 mm。
结论
两组患者的NDI均有显著改善。2L - ACDF组相邻节段椎间盘高度丢失比H - TDR组更大,但差异无统计学意义(p = 0.304)。2L - ACDF组相邻节段的活动度大于H - TDR组(p = 0.003)。这两个结果均支持影像学上的相邻节段退变(ASD),但两组均未出现症状性ASD。
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