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腰椎选择性神经根阻滞术后不久发生急性脑膜炎1例罕见病例报告

A rare case of acute meningitis shortly after lumbar selective nerve root block: a case report.

作者信息

Kim Hyeon-Tae, Lee Joo-Yong, Choi Jung-Hee, Lee Hyung-Min, Park Jin-Wook, Park Ji-In, Shin Young Duck, Choi Young Jin

机构信息

Department of Anesthesiology and Pain Medicine, Chungbuk National University Hospital, College of Medicine, Chungbuk National University Chungcheongbuk-do 28644, Korea.

Department of Surgery, College of Medicine, Chungbuk National University Chungcheongbuk-do 28644, Korea.

出版信息

Am J Transl Res. 2021 Oct 15;13(10):12021-12025. eCollection 2021.

Abstract

A 57-year-old man underwent lumbar selective nerve root block (SNRB) for low back pain and lower radiating pain caused by left-sided L4 disc herniation. He presented to the emergency department with fever, headache and aggravated low back pain approximately 3 hours after the procedure. Infection was suspected; hence, blood tests, cerebrospinal fluid (CSF) tests, lumbar magnetic resonance imaging, and brain computed tomography were performed. Imaging findings were not suggestive of infection. The CSF was turbid and yellowish with pleiocytosis; however, the CSF culture was negative. Based on these findings, the patient was diagnosed with acute meningitis. Broad-spectrum antibiotics and steroid therapy were initiated considering the patient's age and general condition. From hospital day (HD) 2, fever and headache were reduced and disappeared completely by HD 5. At the last follow-up, 1 month after discharge, the patient had no symptoms. Acute meningitis is associated with a high mortality and neurologic deficits. Hence, timely tests, diagnosis, and treatment are critical for positive outcomes. Symptoms of meningitis following a nerve block generally occur within 24-48 hours after the procedure. This case is notable, as it involved a quicker and more sudden onset of symptoms; meningitis occurred only a few hours after lumbar selective nerve root block.

摘要

一名57岁男性因左侧L4椎间盘突出症导致的腰痛和下肢放射性疼痛接受了腰椎选择性神经根阻滞(SNRB)。术后约3小时,他因发热、头痛和腰痛加重而就诊于急诊科。怀疑发生感染,因此进行了血液检查、脑脊液(CSF)检查、腰椎磁共振成像和脑部计算机断层扫描。影像学检查结果未提示感染。脑脊液浑浊且呈淡黄色,有细胞增多现象;然而,脑脊液培养结果为阴性。基于这些发现,该患者被诊断为急性脑膜炎。考虑到患者的年龄和一般状况,开始使用广谱抗生素和类固醇治疗。从住院日(HD)2开始,发热和头痛减轻,并在HD 5时完全消失。在出院后1个月的最后一次随访中,患者没有症状。急性脑膜炎与高死亡率和神经功能缺损有关。因此,及时的检查、诊断和治疗对于取得良好结果至关重要。神经阻滞后脑膜炎的症状通常在术后24 - 48小时内出现。该病例值得注意,因为其症状发作更快且更突然;脑膜炎在腰椎选择性神经根阻滞后仅数小时就发生了。

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