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一名患有多次新冠病毒疾病复发的免疫功能低下患者的恢复期血浆治疗：病例报告

Convalescent plasma therapy in an immunocompromised patient with multiple COVID-19 flares: a case report.

作者信息

Karaolidou Frini, Loutsidi Natasa-Eleni, Mellios Zois, Jahaj Edison, Eleftheriou Konstantinos, Pagoni Maria, Mpaltadakis Ioannis, Dimopoulos Athanasios-Meletios, Kalomenidis Ioannis, Pappas Apostolos G

机构信息

Haematology - Lymphomas Department and Bone Marrow Transplant Unit Evangelismos General Hospital Athens Greece.

Covid-19-Dedicated Ward Evangelismos General Hospital Athens Greece.

出版信息

Respirol Case Rep. 2021 Nov 9;9(12):e0858. doi: 10.1002/rcr2.858. eCollection 2021 Dec.

DOI:10.1002/rcr2.858
PMID:34786202
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8576548/
Abstract

Convalescent plasma (CP) transfusion has been utilized as a salvage therapy in immunocompromised patients with severe COVID-19 pneumonia. We describe the case of a 45-year-old immunocompromised patient, who received CP, in order to control multiple COVID-19 flares and prolonged SARS-CoV-2 viraemia lasting for 2 months after the initial diagnosis.

摘要

恢复期血浆输注已被用作重症新型冠状病毒肺炎免疫功能低下患者的挽救治疗方法。我们描述了一名45岁免疫功能低下患者的病例，该患者接受了恢复期血浆输注，以控制多次新型冠状病毒肺炎病情发作以及初次诊断后持续2个月的严重急性呼吸综合征冠状病毒2病毒血症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9371/8576548/4ed46e9eceed/RCR2-9-e0858-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9371/8576548/4ed46e9eceed/RCR2-9-e0858-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9371/8576548/4ed46e9eceed/RCR2-9-e0858-g002.jpg

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本文引用的文献

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2
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JAMA. 2021 Mar 23;325(12):1185-1195. doi: 10.1001/jama.2021.2747.
3
Convalescent plasma therapy for B-cell-depleted patients with protracted COVID-19.
免疫功能低下的新冠肺炎患者中的新冠病毒2变体：根本原因及未来方向
Transfus Clin Biol. 2022 May;29(2):161-163. doi: 10.1016/j.tracli.2021.12.006. Epub 2021 Dec 29.
COVID-19 病程延长的 B 细胞耗竭患者的恢复期血浆治疗。
Blood. 2020 Nov 12;136(20):2290-2295. doi: 10.1182/blood.2020008423.
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Severe COVID-19-associated pneumonia in 3 patients with systemic sclerosis treated with rituximab.3例接受利妥昔单抗治疗的系统性硬化症患者发生的重症新型冠状病毒肺炎相关肺炎。
Ann Rheum Dis. 2021 Mar;80(3):e37. doi: 10.1136/annrheumdis-2020-217864. Epub 2020 Jun 5.