黑色素瘤患者接受纳武单抗治疗后新发1型糖尿病
New-Onset Type 1 Diabetes Mellitus After Treatment With Nivolumab for Melanoma.
作者信息
Baroud Sarah, Mirza Lubna
机构信息
Department of Internal Medicine, Sheikh Khalifa Medical City, Abu Dhabi, ARE.
Department of Endocrinology, Norman Regional Health System, Norman, USA.
出版信息
Cureus. 2021 Oct 11;13(10):e18679. doi: 10.7759/cureus.18679. eCollection 2021 Oct.
Abstract
A 67-year-old female taking Nivolumab for melanoma developed a hyperglycemic emergency requiring hospital admission. She was referred to our endocrinology clinic post-discharge where she was diagnosed with new-onset Type 1 diabetes mellitus. Severe hyperglycemia and immune-mediated diabetes mellitus are extremely rare but potentially life-threatening side effects of Nivolumab.
摘要
一名67岁的女性因黑色素瘤服用纳武单抗后出现高血糖急症，需要住院治疗。出院后她被转诊至我们的内分泌科门诊，在那里被诊断为新发1型糖尿病。严重高血糖和免疫介导的糖尿病是纳武单抗极为罕见但可能危及生命的副作用。
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