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膀胱小细胞神经内分泌肿瘤:低风险女性中的罕见疾病。

Small-cell neuroendocrine tumor of the bladder: A rare disease in a low-risk woman.

作者信息

Sarver Jordan, Memo Mark

机构信息

Ohio University Heritage College of Osteopathic Medicine, Athens, OH, 45701, United States.

NEOurology, 7430 Southern Blvd, Boardman, OH, 44512, United States.

出版信息

Urol Case Rep. 2021 Oct 29;40:101923. doi: 10.1016/j.eucr.2021.101923. eCollection 2022 Jan.

Abstract

Bladder cancer is the fourth most common malignancy in men and ninth most in woman. Most bladder cancers are urothelial, and the neuroendocrine sub-types make up 0.5-1.0% of cases. Here we present a 70-year-old female with poorly differentiated small cell carcinoma of the bladder who complains of an extensive history of gross hematuria. She was started on a neoadjuvant chemotherapy regimen of 21-day Etoposide with Carboplatin and radical cystectomy. More work needs to be done when it comes to the best treatment method for this rare cohort of patients.

摘要

膀胱癌是男性中第四常见的恶性肿瘤,在女性中排第九。大多数膀胱癌是尿路上皮癌,神经内分泌亚型占病例的0.5 - 1.0%。在此,我们报告一名70岁女性,患有低分化膀胱小细胞癌,主诉有大量肉眼血尿的广泛病史。她开始接受为期21天的依托泊苷联合卡铂新辅助化疗方案及根治性膀胱切除术。对于这一罕见患者群体的最佳治疗方法,仍有更多工作需要开展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d5/8577451/281bfb25b875/gr1.jpg

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