Suppr超能文献

实时动态血糖监测与皮下胰岛素输注治疗 1 型糖尿病患者的血糖控制

Flash glucose monitoring and glycemic control in type 1 diabetes with subcutaneous insulin infusion.

机构信息

Department of Endocrinology, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal.

Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.

出版信息

Acta Diabetol. 2022 Apr;59(4):509-515. doi: 10.1007/s00592-021-01827-2. Epub 2021 Nov 16.

Abstract

AIMS

To analyze the association between scan frequency and glycemic measures in continuous subcutaneous insulin infusion (CSII) treated type 1 diabetes (T1DM) adults.

METHODS

This retrospective study included 140 patients (> 18 years) with T1DM who used flash glucose monitoring (FGM). For each patient, we analyzed the Ambulatory Glucose Profile data over a period of 90 days. Data regarding glucose management indicator (GMI), time above, below and within range (TIR) and coefficient of variation (CV) were correlated with the number of daily scans. The effect of each additional test on glucose parameters was also evaluated.

RESULTS

Users performed a mean of 8.6 ± 4.4 scans per day. There was an inverse correlation between scanning frequency and GMI (r = - 0.431, p < 0.001), CV (r = - 0.440, p < 0.001), time above and below range (r = - 0.446, p < 0.001 and r = - 0.200, p = 0.018, respectively). The number of daily scans correlated positively with TIR (r = 0.554, p < 0.001). For each additional scan per day, the mean GMI decreased 0.09% and TIR increased 1.60%.

CONCLUSIONS

In patients with T1DM and CSII, higher rates of scanning correlated with improved glycemic markers, including reduced GMI and CV and increased TIR. For each test performed, there was a significant effect on the improvement of all glucose parameters.

摘要

目的

分析在接受持续皮下胰岛素输注(CSII)治疗的 1 型糖尿病(T1DM)成人中,扫描频率与血糖测量值之间的关系。

方法

这项回顾性研究纳入了 140 名(年龄>18 岁)使用瞬感血糖监测仪(FGM)的 T1DM 患者。对每位患者,我们在 90 天内分析动态血糖谱数据。将葡萄糖管理指标(GMI)、血糖高于/低于目标范围的时间(TIR)和变异系数(CV)的数据与每日扫描次数相关联。还评估了每次额外测试对血糖参数的影响。

结果

使用者平均每天进行 8.6±4.4 次扫描。扫描频率与 GMI(r=-0.431,p<0.001)、CV(r=-0.440,p<0.001)、血糖高于/低于目标范围的时间(r=-0.446,p<0.001 和 r=-0.200,p=0.018)呈负相关。每日扫描次数与 TIR 呈正相关(r=0.554,p<0.001)。每天增加一次扫描,GMI 平均降低 0.09%,TIR 增加 1.60%。

结论

在接受 CSII 治疗的 T1DM 患者中,更高的扫描频率与改善的血糖指标相关,包括降低 GMI 和 CV 以及增加 TIR。每次测试都对所有血糖参数的改善有显著影响。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验