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组织增强腭成形术治疗腭咽闭合不全

Tissue Augmenting Palatoplasty for the Treatment of Velopharyngeal Insufficiency.

作者信息

Anstadt Erin E, Bruce Madeleine K, Ford Matthew, Jabbour Noel, Pfaff Miles J, Bykowski Michael, Goldstein Jesse A, Losee Joseph E

机构信息

6595Department of Plastic Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

6619Department of Otolaryngology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

出版信息

Cleft Palate Craniofac J. 2022 Dec;59(12):1461-1468. doi: 10.1177/10556656211053761. Epub 2021 Nov 17.

Abstract

PURPOSE

Persistent velopharyngeal insufficiency (VPI) following primary palatoplasty remains a difficult problem to treat. This study evaluates speech outcomes following revision palatoplasty with tissue augmentation using buccal myomucosal flaps (BMF) as an alternative to pharyngoplasty for patients with VPI.

METHODS

A retrospective single-center review of revision palatoplasty with tissue augmentation at a tertiary pediatric hospital Cleft-Craniofacial Center between January 2017 and March 2021 was conducted. Patients with a history of previous palatoplasty, a diagnosis of persistent or recurrent VPI, and comprehensive pre- and postoperative speech evaluations who underwent revision palatoplasty with BMF were included.

RESULTS

Twenty patients met inclusion criteria (35% female, 20% syndromic). Mean age at the time of revision palatoplasty with BMF was 9.7 years. Preoperatively, all patients had stigmatizing speech and received the recommendation for speech surgery; the mean Pittsburgh Weighted Speech Score (PWSS) was 14.3 ± 4.9. The mean postoperative PWSS at the most recent assessment was 4.2 ± 2.3, representing a statistically significant improvement from preoperative scores (< .001). Mean follow-up time was 8.9 months. Following revision palatoplasty with BMF, only one patient has received the recommendation for further speech surgery. No complications were noted.

CONCLUSION

In patients with VPI following primary palatoplasty, revision palatoplasty with tissue augmentation offers an alternative to pharyngoplasty. This approach preserves dynamic velopharyngeal function, improves speech outcomes, and should be considered an option when treating patients with post-primary palatoplasty VPI.

摘要

目的

一期腭裂修复术后持续性腭咽闭合不全(VPI)仍是一个难以治疗的问题。本研究评估了采用颊肌黏膜瓣(BMF)进行组织增容的二期腭裂修复术治疗VPI患者的语音效果,以替代咽成形术。

方法

对2017年1月至2021年3月在一家三级儿科医院颅面裂中心进行组织增容的二期腭裂修复术进行回顾性单中心研究。纳入有一期腭裂修复术史、诊断为持续性或复发性VPI且接受了全面术前和术后语音评估并采用BMF进行二期腭裂修复术的患者。

结果

20例患者符合纳入标准(35%为女性,20%为综合征型)。采用BMF进行二期腭裂修复术时的平均年龄为9.7岁。术前,所有患者均有有缺陷的语音并接受了语音手术建议;匹兹堡加权语音评分(PWSS)平均为14.3±4.9。在最近一次评估中,术后PWSS平均为4.2±2.3,与术前评分相比有统计学显著改善(<0.001)。平均随访时间为8.9个月。采用BMF进行二期腭裂修复术后,只有1例患者接受了进一步语音手术的建议。未观察到并发症。

结论

对于一期腭裂修复术后的VPI患者,采用组织增容的二期腭裂修复术可替代咽成形术。这种方法保留了腭咽的动态功能,改善了语音效果,在治疗一期腭裂修复术后VPI患者时应被视为一种选择。

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