Department of Biotechnology, School of Life Science and Biotechnology, Adamas University, Barasat, Kolkata, West Bengal, India.
Eur Rev Med Pharmacol Sci. 2021 Nov;25(21):6719-6730. doi: 10.26355/eurrev_202111_27117.
COVID-19 vaccines have developed quickly, and vaccination programs have started in most countries to fight the pandemic. The aging population is vulnerable to different diseases, also including the COVID-19. A high death rate of COVID-19 was noted from the vulnerable aging population. A present scenario regarding COVID-19 vaccines and vaccination program foraging adults had been discussed.
This paper reviews the current status and future projections till 2050 of the aging population worldwide. It also discusses the immunosenescence and inflammaging issues facing elderly adults and how it affects the vaccinations such as influenza, pneumococcal, and herpes zoster.
This paper recommends clinical trials for all approved COVID-19 vaccines targeting the elderly adult population and to project a plan to develop a next-generation COVID-19 vaccine.
The review has mapped the COVID-19 vaccination status from the developed and developing countries for the elderly population. Finally, strategies to vaccinate all elderly adults globally against COVID-19 to enhance longevity has been suggested.
COVID-19 疫苗的研发速度很快,大多数国家已经启动了疫苗接种计划以应对这一大流行病。老年人易患各种疾病,包括 COVID-19。脆弱的老年人群体 COVID-19 死亡率很高。本文讨论了目前针对成年人群体的 COVID-19 疫苗和接种计划。
本文回顾了全球老龄化人口的现状和到 2050 年的未来预测。它还讨论了老年人面临的免疫衰老和炎症衰老问题,以及它如何影响流感、肺炎球菌和带状疱疹等疫苗的接种。
本文建议对所有针对老年人群体的已批准 COVID-19 疫苗进行临床试验,并制定计划开发下一代 COVID-19 疫苗。
本文从发达国家和发展中国家的角度描绘了 COVID-19 疫苗为老年人群体接种的现状。最后,建议制定一项策略,为全球所有老年人接种 COVID-19 疫苗,以提高他们的寿命。