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澳大利亚和甘比尔波利尼西亚群岛的HLA及非HLA表型和基因分型

HLA and non-HLA phenotyping and genotyping in Austral and Gambier Polynesian Archipelagos.

作者信息

Dehay C, Gentile B, Jeannet M, Thorsby E, Marcelli-Barge A, Dausset J

机构信息

INSERM U. 93, Hôpital Saint-Louis, Paris, France.

出版信息

Tissue Antigens. 1987 Aug;30(2):49-62. doi: 10.1111/j.1399-0039.1987.tb01597.x.

Abstract

Forty-one individuals from Rurutu Island (Austral Archipelagos) and 41 individuals from the Gambier Archipelagos have been typed for HLA; for blood groups ABO, Rh, MNSs, P, Kell, Kp, Lewis, Lutheran, Kidd; for the electrophoretic systems G6PD, 6-PGD, PGM1, PGM2, AcP, ADA, GPT, Est-D, GLO I, and for the immunoglobulin allotypes Gm and Km. There is a high degree of homogeneity among these Polynesian populations and among other Polynesian populations previously typed. However, small differences exist between the populations of the two archipelagos, possibly due to endogamy or to the smallness of the samples studied. A variant of HLA-Bw22 (called Bw22x) is described.

摘要

对来自鲁鲁图岛(南太平洋群岛)的41人以及来自甘比尔群岛的41人进行了HLA分型;检测了ABO、Rh、MNSs、P、Kell、Kp、Lewis、Lutheran、Kidd血型;检测了G6PD、6-PGD、PGM1、PGM2、AcP、ADA、GPT、Est-D、GLO I电泳系统;检测了免疫球蛋白同种异型Gm和Km。这些波利尼西亚人群以及之前分型的其他波利尼西亚人群具有高度同质性。然而,这两个群岛的人群之间存在细微差异,可能是由于近亲通婚或所研究样本量较小所致。描述了一种HLA-Bw22变体(称为Bw22x)。

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