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L-色氨酸和5-羟色氨酸治疗抑郁症的综述

L-tryptophan and 5-hydroxytryptophan in the treatment of depression. A review.

作者信息

d'Elia G, Hanson L, Raotma H

出版信息

Acta Psychiatr Scand. 1978 Mar;57(3):239-52. doi: 10.1111/j.1600-0447.1978.tb06890.x.

DOI:10.1111/j.1600-0447.1978.tb06890.x
PMID:347886
Abstract

Trials performed do not provide evidence for an antidepressant effect of 5-HTP. L-TP, without interacting pharmaca, does not appear to be a well-documented antidepressant. The only convincing evidence for L-TP as an antidepressant is that L-TP enhances the effect of MAOI.

摘要

已进行的试验未提供5-羟色氨酸具有抗抑郁作用的证据。在不与其他药物相互作用的情况下,左旋色氨酸似乎并不是一种有充分文献记载的抗抑郁药。左旋色氨酸作为抗抑郁药的唯一令人信服的证据是它能增强单胺氧化酶抑制剂的效果。

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Tryptophan and 5-hydroxytryptophan for depression.色氨酸和5-羟色氨酸治疗抑郁症。
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PLoS One. 2009 Aug 27;4(8):e6797. doi: 10.1371/journal.pone.0006797.
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Tryptophan and 5-hydroxytryptophan for depression.色氨酸和5-羟色氨酸治疗抑郁症。
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Tryptophan tolerance and metabolism in endogenous depression.内源性抑郁症中色氨酸的耐受性与代谢
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Eur J Clin Pharmacol. 1981;21(2):137-42. doi: 10.1007/BF00637514.
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