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狂犬病疫苗接种后发生的超急性脑脊髓炎

[Hyperacute encephalomyelitis following lyssa vaccination].

作者信息

Varga S M, Szabó I, Balázs L

出版信息

Morphol Igazsagugyi Orv Sz. 1979 Jan;19(1):27-31.

PMID:34789
Abstract

UNLABELLED

A case of hyperacute disseminated encephalomyelitis following lyssa-vaccination is reported. Clinical symptoms occurred on the tenth day after the vaccination and the patient died three days afterward. Demyelinization and glia proliferation was observed histologically in the spinal cord. No alterations could be seen in the peripheric nerves.

CONCLUSIONS

  1. The spinal and cerebral forms of the postvaccinial encephalomyelitis can not be sharply distinguished. 2. In the postvaccinial encephalomyelitis there are also severe infiltration, demyelinization and gliosis in the opticus. 3. Post-vaccinial lyssa encephalomyelitis is a rare, but unavoidable complication of the lassa-vaccination. 4. The State Insurance Company have to pay damages.
摘要

未标记

报告了1例狂犬病疫苗接种后发生的超急性播散性脑脊髓炎病例。临床症状在接种疫苗后第10天出现,患者3天后死亡。组织学观察发现脊髓有脱髓鞘和胶质细胞增生。周围神经未见改变。

结论

  1. 疫苗接种后脑脊髓炎的脊髓型和脑型无法明确区分。2. 疫苗接种后脑脊髓炎的视神经也有严重浸润、脱髓鞘和胶质增生。3. 接种疫苗后狂犬病脑脊髓炎是狂犬病疫苗接种的一种罕见但不可避免的并发症。4. 国家保险公司必须支付赔偿金。

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