Knapp D E, Crosby D L, Burke L B, Dreis M W, Forbes M B, Knapp D A
Am J Hosp Pharm. 1978 Apr;35(4):437-40.
A manual drug use review (DUR) methodology to screen outpatient prescribing which would meet the needs of large third-party programs that cannot afford elaborate computerized DUR was developed and pilot tested. A Medicaid drugs data base was used for the pilot test. A probability sample of 100 recipients over a three-month period was selected for the DUR. The drugs for each recipient, listed by their generic composition and amount, were recorded. Then a priori, explicit, screening criteria were developed for these generics. These criteria delineated drugs of choice, daily dose and refill patterns and, as appropriate, therapy length, drug holidays, and disease-drug and drug-drug interactions. Only 11% of recipients had prescribing patterns which passed all the screens. The most frequent screening failure was due to the prescribing of a drug which was not a drug of choice. In nearly all of the cases which failed the other screens, an alert pharmacist with patient records should have noticed these problems. An analysis showed that the initial start-up cost for the manual DUR was estimated at $1053 (not including personnel fringe benefits); for subsequent quarterly review, the cost was estimated to be about $530. The project showed that manual DUR can effectively and efficiently screen prescribing in a large third-party program.
开发并进行了试点测试一种手动药物使用审查(DUR)方法,用于筛查门诊处方,该方法能够满足那些负担不起复杂计算机化DUR的大型第三方项目的需求。试点测试使用了医疗补助药物数据库。在三个月的时间里,从接受者中选取了100个概率样本用于DUR。记录了每个接受者按通用成分和数量列出的药物。然后针对这些通用药物制定了先验的、明确的筛查标准。这些标准划定了首选药物、每日剂量和再填充模式,并酌情规定了治疗时长、药物假期以及疾病-药物和药物-药物相互作用。只有11%的接受者的处方模式通过了所有筛查。最常见的筛查失败原因是开出了非首选药物。在几乎所有未能通过其他筛查的病例中,配备患者记录的警觉药剂师本应注意到这些问题。一项分析表明,手动DUR的初始启动成本估计为1053美元(不包括人员附加福利);后续季度审查的成本估计约为530美元。该项目表明,手动DUR能够在大型第三方项目中有效且高效地筛查处方。