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十年回顾性分析:发展中国家一家三级医院产妇心搏骤停的发生率、特征、病因和结局。

A ten-year retrospective review of maternal cardiac arrest: Incidence, characteristics, causes, and outcomes in a tertiary-care hospital in a developing country.

机构信息

Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.

Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.

出版信息

Taiwan J Obstet Gynecol. 2021 Nov;60(6):999-1004. doi: 10.1016/j.tjog.2021.09.009.

Abstract

OBJECTIVE

Maternal cardiac arrest is rare. We retrospectively reviewed and reported (1) the incidence of maternal cardiac arrests during admissions for delivery; (2) the characteristics and causes of cardiac arrest; and (3) the mortality rate and outcomes in a referral, single-university, teaching hospital in Thailand.

MATERIALS AND METHODS

Data on 23 cardiac arrests during admissions for delivery in the decade January 2006-December 2015 were retrospectively chart-reviewed. Patients with gestational ages under 24 weeks or cardiac arrests and death occurring before hospital arrival were excluded. The clinical characteristics of the arrests and outcomes were collected.

RESULTS

Of 89,368 deliveries during the decade, 23 women suffered cardiac arrest (incidence, 1:3885), with 3 of those arrests occurring before delivery (incidence, 1:29,789). One patient underwent a perimortem cesarean delivery in the operating theatre. The most common reasons for the arrests were hypertension during pregnancy and cardiovascular causes (30.4% and 21.7%, respectively). Amniotic fluid embolisms were suspected for 2 patients (8.7%) with unidentified causes. The incidence of maternal deaths in peripartum cardiac arrests was 20/23, representing 86.9% (95% CI, 67.9-95.5) or 1:4468 of deliveries. Three patients suffering cardiac arrests after delivery survived to discharge.

CONCLUSIONS

We found a high maternal mortality rate following cardiac arrests during hospitalization for delivery. To decrease the incidence of arrests during the peripartum period and diminish the maternal mortality rate, identification of the causes and precipitating factors is vital. High-risk pregnant women require multidisciplinary care to improve the survival-to-discharge rate.

摘要

目的

产妇心搏骤停较为罕见。我们回顾性地分析并报告了(1)在分娩住院期间产妇心搏骤停的发生率;(2)心搏骤停的特征和原因;以及(3)在泰国一家转诊的、单一大学、教学医院的死亡率和结局。

材料和方法

回顾性地分析了 2006 年 1 月至 2015 年 12 月期间在分娩住院期间发生的 23 例心搏骤停患者的数据。排除了孕周<24 周或心搏骤停和死亡发生在入院前的患者。收集了心搏骤停的临床特征和结局。

结果

在这十年中,89368 例分娩中有 23 例产妇发生心搏骤停(发生率为 1:3885),其中 3 例发生在分娩前(发生率为 1:29789)。1 例患者在手术室进行了围产儿紧急剖宫产。最常见的原因是妊娠高血压和心血管原因(分别占 30.4%和 21.7%)。有 2 例(8.7%)患者疑似羊水栓塞,原因不明。围产期心搏骤停产妇死亡的发生率为 20/23,占 86.9%(95%CI,67.9-95.5)或 1:4468 分娩。3 例分娩后心搏骤停的患者存活出院。

结论

我们发现分娩住院期间心搏骤停后的产妇死亡率很高。为了降低围产期心搏骤停的发生率和降低产妇死亡率,确定病因和诱发因素至关重要。高危孕妇需要多学科护理,以提高存活率。

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