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Covid-19 病例系列中的肠穿孔。

Bowel Perforation in Covid-19 Case Series.

出版信息

Ann Ital Chir. 2021;92:589-591.

PMID:34795115
Abstract

OBJECTIVE

To describe the clinical characteristics and outcomes of patients with coronavirus disease 2019(COVID-19) who developed bowel perforation.

MATERIALS AND METHODS

This case series was conducted in Emergency Department of AORN Sant'Anna and S. Sebastiano located in Caserta. All patients resulted positive to SARS-Cov-2 in nasopharyngeal swabs whith a positive laboratory test for SARS-CoV-2 from real time reverse transcription polymerase chain reaction(RT-PCR) as well as bowel perforation which was identified by abdominal CT, from September 2020 to December 2020.

RESULTS

A total of five patients were identified with Bowel perforation occurred despite all patients being on anticoagulation. All patients were Italian, predominantly male(four patients) with an average age of 60 years and the most common comorbidity was hypertension, diabetes and obesity.

DISCUSSION

Bowel perforation in COVID-19 is clinically significant with high morbidity and mortality. In our series 40% of patients who were diagnosed of bowel perforation died. Average time to death after bowel perforation diagnosis was 6 days.

CONCLUSION

We describe a case series of COVID-19 patients who developed bowel perforation.

KEY WORDS

Covid-19, Bowel perforation.

摘要

目的

描述发生肠穿孔的 2019 年冠状病毒病(COVID-19)患者的临床特征和结局。

材料与方法

本病例系列研究在位于卡塞塔的 AORN Sant'Anna 和 S. Sebastiano 的急诊部进行。所有患者的鼻咽拭子均对 SARS-CoV-2 呈阳性,并且 SARS-CoV-2 的实时逆转录聚合酶链反应(RT-PCR)实验室检测也呈阳性,同时通过腹部 CT 确定发生了肠穿孔,这些患者均来自 2020 年 9 月至 2020 年 12 月。

结果

共发现 5 例肠穿孔患者,尽管所有患者均接受抗凝治疗。所有患者均为意大利人,主要为男性(4 例),平均年龄为 60 岁,最常见的合并症是高血压、糖尿病和肥胖症。

讨论

COVID-19 中的肠穿孔具有较高的发病率和死亡率,临床上意义重大。在我们的研究系列中,40%的肠穿孔患者死亡。肠穿孔诊断后的平均死亡时间为 6 天。

结论

我们描述了一组发生肠穿孔的 COVID-19 患者的病例系列。

关键词

Covid-19;肠穿孔。

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