• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

涉及有性-无性周期的倍性基因流促进了异育银鲫的多样化。

Interploidy gene flow involving the sexual-asexual cycle facilitates the diversification of gynogenetic triploid Carassius fish.

机构信息

Laboratory of Animal Ecology, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan.

Laboratory for Chromosome Segregation, RIKEN Center for Biosystems Dynamics Research, Chuo-ku, Kobe, 650-0047, Japan.

出版信息

Sci Rep. 2021 Nov 18;11(1):22485. doi: 10.1038/s41598-021-01754-w.

DOI:10.1038/s41598-021-01754-w
PMID:34795357
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8602411/
Abstract

Asexual vertebrates are rare and at risk of extinction due to their restricted adaptability through the loss of genetic recombination. We explore the mechanisms behind the generation and maintenance of genetic diversity in triploid asexual (gynogenetic) Carassius auratus fish, which is widespread in East Asian fresh waters and exhibits one of the most extensive distribution among asexual vertebrates despite its dependence on host sperm. Our analyses of genetic composition using dozens of genetic markers and genome-wide transcriptome sequencing uncover admixed genetic composition of Japanese asexual triploid Carassius consisting of both the diverged Japanese and Eurasian alleles, suggesting the involvement of Eurasian lineages in its origin. However, coexisting sexual diploid relatives and asexual triploids in Japan show regional genetic similarity in both mitochondrial and nuclear markers. These results are attributed to a unique unidirectional gene flow from diploids to sympatric triploids, with the involvement of occasional sexual reproduction. Additionally, the asexual triploid shows a weaker population structure than the sexual diploid, and multiple triploid lineages coexist in most Japanese rivers. The generated diversity via repeated interploidy gene flow as well as an increased establishment of immigrants is assumed to offset the cost of asexual reproduction and might contribute to the successful broad distribution of this asexual vertebrate.

摘要

有性生殖的脊椎动物较为罕见，且由于遗传重组的丧失，其适应性受到限制，面临灭绝的风险。我们探索了三倍体（雌核发育）鲤鱼中遗传多样性产生和维持的机制，这种鲤鱼广泛分布于东亚淡水水域，尽管其依赖宿主精子，但在有性脊椎动物中分布最为广泛。我们使用数十个遗传标记和全基因组转录组测序对遗传组成进行了分析，发现日本三倍体无融合生殖鲤鱼的遗传组成是由日本和欧亚分化的等位基因混合而成，这表明欧亚谱系参与了其起源。然而，在日本共存的有性二倍体亲属和三倍体无融合生殖体在线粒体和核标记上表现出区域遗传相似性。这些结果归因于从二倍体到同域三倍体的单向基因流，偶尔涉及有性繁殖。此外，三倍体无融合生殖的种群结构比有性二倍体弱，而且大多数日本河流中存在多个三倍体谱系。通过反复的倍间基因流产生的多样性以及移民的增加，被认为可以抵消有性生殖的代价，并有助于这种无性生殖脊椎动物的广泛分布。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/ad43172b5aca/41598_2021_1754_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/f1c118c5767c/41598_2021_1754_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/90d500a02ba3/41598_2021_1754_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/237ce1f14ce6/41598_2021_1754_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/203e15eefcb7/41598_2021_1754_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/ad43172b5aca/41598_2021_1754_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/f1c118c5767c/41598_2021_1754_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/90d500a02ba3/41598_2021_1754_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/237ce1f14ce6/41598_2021_1754_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/203e15eefcb7/41598_2021_1754_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35c/8602411/ad43172b5aca/41598_2021_1754_Fig5_HTML.jpg

相似文献

1
Interploidy gene flow involving the sexual-asexual cycle facilitates the diversification of gynogenetic triploid Carassius fish.涉及有性-无性周期的倍性基因流促进了异育银鲫的多样化。
Sci Rep. 2021 Nov 18;11(1):22485. doi: 10.1038/s41598-021-01754-w.
2
Origin of scarlet gynogenetic triploid Carassius fish: Implications for conservation of the sexual-gynogenetic complex. Scarlet 雌核发育三倍体鲤鱼的起源：对性-雌核发育复合体保护的启示。
PLoS One. 2022 Oct 20;17(10):e0276390. doi: 10.1371/journal.pone.0276390. eCollection 2022.
3
High male incidence and evolutionary implications of triploid form in northeast Asia Carassius auratus complex.东北亚鲤鱼复合体中三倍体形式的高雄性发生率及其进化意义。
Mol Phylogenet Evol. 2013 Jan;66(1):350-9. doi: 10.1016/j.ympev.2012.10.006. Epub 2012 Oct 23.
4
MHC genes and parasitism in Carassius gibelio, a diploid-triploid fish species with dual reproduction strategies.MHC 基因与二倍体-三倍体鱼类鲫（Carassius gibelio）的寄生关系，鲫具有双重繁殖策略。
BMC Evol Biol. 2013 Jun 14;13:122. doi: 10.1186/1471-2148-13-122.
5
Identification of triploid individuals and clonal lines in Carassius auratus complex using microsatellites.利用微卫星鉴定金鱼复合种群中的三倍体个体和克隆系。
Int J Biol Sci. 2011 Mar 18;7(3):279-85. doi: 10.7150/ijbs.7.279.
6
Biogeography and evolution of the Carassius auratus-complex in East Asia.东亚鲤鱼属复合体的生物地理学与进化。
BMC Evol Biol. 2010 Jan 12;10:7. doi: 10.1186/1471-2148-10-7.
7
Genetic responses in sexual diploid and unisexual triploid goldfish (Carassius auratus) introduced into a high-altitude environment.引入高海拔环境的有性二倍体和单性三倍体金鱼（Carassius auratus）的遗传反应。
Mol Ecol. 2023 Apr;32(8):1955-1971. doi: 10.1111/mec.16864. Epub 2023 Feb 10.
8
Reproduction-associated pathways in females of gibel carp (Carassius gibelio) shed light on the molecular mechanisms of the coexistence of asexual and sexual reproduction.雌鱼生殖相关途径揭示了两性生殖共存的分子机制。
BMC Genomics. 2024 Jun 1;25(1):548. doi: 10.1186/s12864-024-10462-4.
9
Recent invasion and low level of divergence between diploid and triploid forms of Carassius auratus complex in Croatia.克罗地亚鲫属复合体二倍体和三倍体形式之间最近的入侵及低水平分化。
Genetica. 2011 Jun;139(6):789-804. doi: 10.1007/s10709-011-9584-y. Epub 2011 Jun 7.
10
Evaluation of elevated ploidy and asexual reproduction as alternative explanations for geographic parthenogenesis in Eucypris virens ostracods.评估多倍体和无性繁殖是否是东方真象鼻蚤介形类地理孤雌生殖的替代解释。
Evolution. 2010 Apr 1;64(4):986-97. doi: 10.1111/j.1558-5646.2009.00872.x. Epub 2009 Oct 23.

引用本文的文献

1
Spatio-Temporal Patterns of Hybridization in an Alloploid Salamander (Ambystomatidae: ) and Conservation Implications of Introgression in a Unisexual Vertebrate.异源多倍体蝾螈（钝口螈科： ）杂交的时空模式及单性脊椎动物基因渗入的保护意义
Ecol Evol. 2025 Jan 26;15(1):e70765. doi: 10.1002/ece3.70765. eCollection 2025 Jan.
2
Origin of scarlet gynogenetic triploid Carassius fish: Implications for conservation of the sexual-gynogenetic complex. Scarlet 雌核发育三倍体鲤鱼的起源：对性-雌核发育复合体保护的启示。
PLoS One. 2022 Oct 20;17(10):e0276390. doi: 10.1371/journal.pone.0276390. eCollection 2022.
3
Changes in Ploidy Drive Reproduction Transition and Genomic Diversity in a Polyploid Fish Complex.

本文引用的文献

1
A Tripolar Spindle Formed at Meiosis I Assures the Retention of the Original Ploidy in the Gynogenetic Triploid Crucian Carp, Ginbuna Carassius auratus langsdorfii: (fish oocytes/gynogenesis/meiosis/spindle formation/histone H1 kinase).减数分裂I期形成的三极纺锤体确保雌核发育三倍体鲫鱼（银鲫，Carassius auratus langsdorfii）维持原始倍性：（鱼类卵母细胞/雌核发育/减数分裂/纺锤体形成/组蛋白H1激酶）
Dev Growth Differ. 1993 Dec;35(6):631-636. doi: 10.1111/j.1440-169X.1993.00631.x.
2
Sex chromosomes in meiotic, hemiclonal, clonal and polyploid hybrid vertebrates: along the 'extended speciation continuum'.有性生殖、半克隆、克隆和多倍体杂交脊椎动物中的性染色体：沿着“扩展的物种形成连续体”。
Philos Trans R Soc Lond B Biol Sci. 2021 Sep 13;376(1833):20200103. doi: 10.1098/rstb.2020.0103. Epub 2021 Jul 26.
3
多倍体鱼类复合体中倍性驱动生殖转变和基因组多样性的变化。
Mol Biol Evol. 2022 Sep 1;39(9). doi: 10.1093/molbev/msac188.
4
Equilibrated evolution of the mixed auto-/allopolyploid haplotype-resolved genome of the invasive hexaploid Prussian carp.混合自交/异源多倍体单倍型解析基因组的平衡进化，入侵六倍体鲫鱼。
Nat Commun. 2022 Jul 14;13(1):4092. doi: 10.1038/s41467-022-31515-w.
Fixation of allelic gene expression landscapes and expression bias pattern shape the transcriptome of the clonal Amazon molly.等位基因表达景观和表达偏倚模式的固定塑造了克隆亚马逊丽鱼的转录组。
Genome Res. 2021 Mar;31(3):372-379. doi: 10.1101/gr.268870.120. Epub 2021 Feb 5.
4
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research.ARRIVE 指南 2.0：报告动物研究的更新指南。
PLoS Biol. 2020 Jul 14;18(7):e3000410. doi: 10.1371/journal.pbio.3000410. eCollection 2020 Jul.
5
Evolutionary dynamics of 18S and 5S rDNA in autotriploid Carassius auratus.18S 和 5S rDNA 在同源三倍体鲫鱼中的进化动态。
Gene. 2020 May 5;737:144433. doi: 10.1016/j.gene.2020.144433. Epub 2020 Jan 31.
6
De novo assembly of the goldfish () genome and the evolution of genes after whole-genome duplication.金鱼基因组从头组装及全基因组复制后基因的进化。
Sci Adv. 2019 Jun 26;5(6):eaav0547. doi: 10.1126/sciadv.aav0547. eCollection 2019 Jun.
7
Unexpected Oogenic Pathways for the Triploid Fish Chrosomus eos-neogaeus.三倍体鱼类 Chrosomus eos-neogaeus 的意外卵发生途径。
J Hered. 2019 May 7;110(3):370-377. doi: 10.1093/jhered/esy072.
8
fastp: an ultra-fast all-in-one FASTQ preprocessor.fastp：一个超快速的一体化 FASTQ 预处理程序。
Bioinformatics. 2018 Sep 1;34(17):i884-i890. doi: 10.1093/bioinformatics/bty560.
9
Clonal polymorphism and high heterozygosity in the celibate genome of the Amazon molly.亚马逊丽体鱼的孤雌生殖基因组中的克隆多态性和高度杂合性。
Nat Ecol Evol. 2018 Apr;2(4):669-679. doi: 10.1038/s41559-018-0473-y. Epub 2018 Feb 12.
10
MUTATION LOAD AND THE SURVIVAL OF SMALL POPULATIONS.突变负荷与小种群的生存
Evolution. 1990 Nov;44(7):1725-1737. doi: 10.1111/j.1558-5646.1990.tb05244.x.