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烯丙孕素对未同步化马胚胎受体维持妊娠的影响。

Effect of altrenogest on pregnancy maintenance in unsynchronized equine embryo recipients.

作者信息

Parry-Weeks L C, Holtan D W

机构信息

Department of Animal Science, Oregon State University, Corvallis 97331.

出版信息

J Reprod Fertil Suppl. 1987;35:433-8.

PMID:3479598
Abstract

Non-surgical embryo recovery attempts were done on Day 7 after ovulation. Embryo recovery rate from mares of varied reproductive histories was 57% (38/67). Non-surgical transfer of these embryos into altrenogest-treated recipient mares that ovulated between 3 days before and 3 days after the donor resulted in a 30-day pregnancy rate of 77% (10/13). Transfer of embryos into altrenogest-treated recipients that ovulated between 4 days before and 6 days after the donor resulted in an overall pregnancy rate of 64% (16/25) at Day 30 of gestation. No recipients that were in oestrus at the start of treatment, nor recipients that ovulated 5 or more days before the donor, maintained pregnancy. Mean plasma progesterone concentrations of pregnant, altrenogest-treated, embryo-recipient mares; pregnant, altrenogest-treated, untransferred mares; and pregnant, untreated, untransferred mares were comparable (P greater than 0.05). Treatment of embryo-recipient mares with altrenogest appears to be beneficial in extending the degree of donor-recipient synchrony required for successful embryo transfer. Altrenogest treatment also seems to be conductive to pregnancy maintenance in recipients experiencing luteal dysfunction.

摘要

在排卵后第7天进行非手术胚胎回收尝试。不同繁殖史母马的胚胎回收率为57%(38/67)。将这些胚胎非手术移植到在供体母马排卵前3天至排卵后3天之间排卵且经烯丙孕素处理的受体母马中,30天的妊娠率为77%(10/13)。将胚胎移植到在供体母马排卵前4天至排卵后6天之间排卵且经烯丙孕素处理的受体母马中,在妊娠第30天时总体妊娠率为64%(16/25)。在治疗开始时处于发情期的受体母马,以及在供体母马排卵前5天或更早排卵的受体母马,均未维持妊娠。经烯丙孕素处理的妊娠胚胎受体母马、经烯丙孕素处理的未移植妊娠母马以及未处理的未移植妊娠母马的平均血浆孕酮浓度相当(P>0.05)。用烯丙孕素处理胚胎受体母马似乎有利于扩大成功进行胚胎移植所需的供体 - 受体同步程度。烯丙孕素处理似乎也有助于黄体功能不全的受体母马维持妊娠。

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Effect of altrenogest on pregnancy maintenance in unsynchronized equine embryo recipients.烯丙孕素对未同步化马胚胎受体维持妊娠的影响。
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