Nasreen Shagufta, Ali Nadir, Ahmad Tanveer, Mazcuri Misauq, Abid Ambreen, Thapaliya Pratikshya
Thoracic Surgery, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Cureus. 2021 Oct 14;13(10):e18781. doi: 10.7759/cureus.18781. eCollection 2021 Oct.
Introduction Managing chronic empyema thoracis (CET) due to tuberculosis (TB) in debilitated patients is complicated. Open window thoracostomy (OWT) is one of the ways to manage these high-risk patients. Closure of OWT is sometimes difficult to attain. The purpose of this study is to compare the outcome of OWT in terms of chest wall closure in two similar groups. The only difference between these groups was the circumference of the OWT created. This study will benefit patients of CET with OWT to attain early chest wall closure without being subjected to another surgical trauma. Methods This is a prospective comparative study, conducted in the Department of Thoracic Surgery, Jinnah Postgraduate Medical Centre, Karachi, from August 2019 to July 2020. A total of 48 patients, 22 and 26 patients in group A and group B, respectively, were included in this study. Both groups were matched for age, gender, diagnosis, body mass index, and stage of empyema, with the difference only in the OWT circumference. Results Both groups had a history of multiple chest tube intubations. Among group A patients, a smaller circumference of OWT (20-24 cm; mean 22 cm) was created as compared to group B (30-34 cm; mean 33 cm). Spontaneous OWT closure was seen in 21 (95.5%) patients in group A and seven (26.9%) patients in group B in a time period of 6.2 ± 1.5 and 11.4 ± 0.5 months, respectively (p-value: ≤ 0.001). Pleural cavity clearance was attained in 21 (95.5%) patients in group A and 24 (92.35%) patients in group B in a time duration of 4 ± 1.4 months and 4 ± 4.1 months, respectively (p-value: ≤ 0.97). Complete lung expansion was found in 21 (95.5%) patients in group A and 24 (92.3%) patients in group B in a time duration of 5 ± 1.7 months and 4.7 ± 1.6 months, respectively (p-value: ≤ 0.62). Conclusion This prospective single-center study shows that successful spontaneous early closure of OWT primarily depends on the size of the OWT created. A smaller-sized OWT, if created judiciously, not only closes spontaneously but also facilitates the clearance of purulent discharge and potentially helps in the definitive healing of bronchopleural fistulae and consequent lung expansion, thereby avoiding more invasive procedures like decortication in a debilitated patient. Furthermore, there is no need for a second surgery for closure of OWT.
引言
在身体虚弱的患者中,处理因结核病(TB)导致的慢性脓胸(CET)是复杂的。开窗胸廓造口术(OWT)是管理这些高危患者的方法之一。有时难以实现OWT的闭合。本研究的目的是比较两个相似组在胸廓闭合方面OWT的结果。这些组之间的唯一区别是所创建的OWT的周长。本研究将使接受OWT治疗的CET患者受益,以实现早期胸廓闭合,而无需遭受另一次手术创伤。
方法
这是一项前瞻性比较研究,于2019年8月至2020年7月在卡拉奇真纳研究生医学中心胸外科进行。本研究共纳入48例患者,A组22例,B组26例。两组在年龄、性别、诊断、体重指数和脓胸分期方面进行了匹配,仅OWT周长存在差异。
结果
两组患者均有多次胸腔插管史。与B组(30 - 34 cm;平均33 cm)相比,A组患者创建的OWT周长较小(20 - 24 cm;平均22 cm)。在6.2±1.5个月和11.4±0.5个月的时间段内,A组21例(95.5%)患者和B组7例(26.9%)患者的OWT实现了自发闭合(p值:≤0.001)。在4±1.4个月和4±4.1个月的时间段内,A组21例(95.5%)患者和B组24例(92.35%)患者的胸腔积液得到清除(p值:≤0.97)。在5±1.7个月和4.7±1.6个月的时间段内,A组21例(95.5%)患者和B组24例(92.3%)患者的肺完全复张(p值:≤0.62)。
结论
这项前瞻性单中心研究表明,OWT成功自发早期闭合主要取决于所创建的OWT的大小。如果谨慎创建较小尺寸的OWT,不仅能自发闭合,还能促进脓性分泌物的清除,并可能有助于支气管胸膜瘘的最终愈合以及随之而来的肺复张,从而避免在身体虚弱的患者中进行如胸膜剥脱术等更具侵入性的手术。此外,无需进行第二次手术来闭合OWT。