Reyes K G, Mason D P, Murthy S C, Su J W, Rice T W
Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH, USA.
Thorac Cardiovasc Surg. 2010 Jun;58(4):220-4. doi: 10.1055/s-0029-1240972. Epub 2010 May 31.
In modern day thoracic surgical practice, better understanding of the pathophysiology of intrathoracic infections, improved antibiotic therapy and advancements in thoracic surgical techniques have decreased the use of procedures such as open window thoracostomy (OWT). Despite this, there are occasions where OWT cannot be avoided, and it is of interest where its current utility lies. To determine the current efficacy of OWT, we reviewed our recent experience with a focus on the indications, timing of surgery, effectiveness in clearing infection, patient survival, and timing of closure.
After Institutional Review Board approval, charts of 78 patients were reviewed. Dates reviewed were from 1/1/1998 to 1/1/2008. Patients were predominantly male (66 %) with a median age 58 years. Median time from initial diagnosis to OWT was 70 days (range 1 to 720 days).
Primary indication for surgery was empyema in 75 (96 %), and most patients had previous thoracic surgery. The most frequent causes of empyema were post-pneumonectomy (n = 25), post-pneumonic (n = 14), and post-lobectomy (n = 9). Bronchopleural fistulae were present in 29 (37 %) cases. Lung cancer was diagnosed in 34 (45 %) patients, and 24 underwent perioperative radiation therapy. Patient survival at 1 month, 6 months, 1 year and 5 years was 94 %, 82 %, 74 % and 60 %, respectively, with an in-hospital mortality of 6.4 %. Infection was controlled in nearly all patients (n = 72). Fifteen (19 %) patients underwent surgical closure for OWT; in 2 (2.6 %), OWT closed spontaneously.
Currently, open window thoracostomy is used to treat complex empyema incurred from pulmonary resection, cancer and/or infection in patients that cannot be managed by more conservative strategies. Overall mortality and morbidity rates are acceptable in this debilitated patient group.
在现代胸外科手术实践中,对胸腔内感染病理生理学的更好理解、抗生素治疗的改进以及胸外科技术的进步减少了诸如开窗胸廓造口术(OWT)等手术的使用。尽管如此,仍有一些情况无法避免进行OWT,其目前的应用价值备受关注。为了确定OWT的当前疗效,我们回顾了近期经验,重点关注手术指征、手术时机、清除感染的效果、患者生存率以及关闭时机。
经机构审查委员会批准后,对78例患者的病历进行了回顾。回顾日期为1998年1月1日至2008年1月1日。患者以男性为主(66%),中位年龄58岁。从初始诊断到OWT的中位时间为70天(范围1至720天)。
手术的主要指征是脓胸,共75例(96%),大多数患者曾接受过胸外科手术。脓胸最常见的原因是肺切除术后(n = 25)、肺炎后(n = 14)和肺叶切除术后(n = 9)。29例(37%)患者存在支气管胸膜瘘。34例(45%)患者诊断为肺癌,24例接受了围手术期放射治疗。1个月、6个月、1年和5年的患者生存率分别为94%、82%、74%和60%,住院死亡率为6.4%。几乎所有患者(n = 72)的感染均得到控制。15例(19%)患者接受了OWT手术关闭;2例(2.6%)患者的OWT自行关闭。
目前,开窗胸廓造口术用于治疗因肺切除、癌症和/或感染导致的复杂脓胸,这些患者无法采用更保守的策略进行治疗。在这个虚弱的患者群体中,总体死亡率和发病率是可以接受的。