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环糊精控制释放综述:释放方法、释放体系及应用。

A review of controlled release from cyclodextrins: release methods, release systems and application.

机构信息

School of Food Science and Technology, Jiangnan University, Wuxi, People's Republic of China.

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, People's Republic of China.

出版信息

Crit Rev Food Sci Nutr. 2023;63(20):4744-4756. doi: 10.1080/10408398.2021.2007352. Epub 2021 Nov 19.

DOI:10.1080/10408398.2021.2007352
PMID:34797201
Abstract

The controlled release of guest molecules from cyclodextrin (CD) inclusion complexes is very important for specific industrial applications in foods, medicine, cosmetics, textiles, agriculture, environmental protection, and chemical materials. The term "controlled release" encompasses several related methods, including those referred to as immediate release, sustained release and targeted release. Many different CD-based controlled release systems are currently used in practical applications. CD inclusion complexes, CD coupling, supramolecular hydrogels, and supramolecular micelles are among the most common. This review systematically introduces the principles and applications of CD-based controlled release systems, providing a theoretical basis for improving the bioavailability of effective substances and broadening their range of application.

摘要

客体分子从环糊精(CD)包合物中的控制释放对于食品、医药、化妆品、纺织品、农业、环境保护和化学材料等特定工业应用非常重要。“控制释放”一词涵盖了几种相关的方法,包括所谓的速释、缓释和靶向释放。目前许多不同的基于 CD 的控制释放系统都在实际应用中使用。CD 包合物、CD 偶联、超分子水凝胶和超分子胶束是最常见的几种。本文系统介绍了基于 CD 的控制释放系统的原理和应用,为提高有效物质的生物利用度和拓宽其应用范围提供了理论依据。

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