Beidas Khalid F, Sawan Hasan, Alwatban Fahad, AlHazzazi Khalid, Beidas Tala
Security Forces Hospital Program, Saudi Arabia.
King Fahad Medical City Orthopedic Department, Saudi Arabia.
Int J Surg Case Rep. 2021 Dec;89:106575. doi: 10.1016/j.ijscr.2021.106575. Epub 2021 Nov 6.
Hibernomas are rare, slow-growing, painless, benign tumors of soft tissue that develop from residual brown fat cell showing predilection for areas where brown fat is more common in fetuses and infants. Due to the rarity of the tumor its often overlooked or mistaken for other pathologies such as liposarcoma.
Using the CARE 2020 criteria we describe a 26-year-old man who presented with painful swelling of the thigh. A magnetic resonance imaging examination without contrast showed a mass in the medial thigh just lateral to the femoral artery. A biopsy specimen was obtained from his thigh for histopathological analysis, and the findings suggested a hibernoma. A wide resection was performed, and it showed that the femoral nerve was lateral to the mass, with the course of the nerve altered due to mass effect. The mass was sent for a histopathological examination, and the findings were consistent with a hibernoma. Two weeks post-operative, the patient reported a considerable decrease in pain intensity, and six months post-operative, he reported complete pain relief.
Hibernomas are unusual tumors that are benign and usually painless, but the large size the tumor can reach and proximity to vital structures can explain the growing trends symptomatic nature of some hibernomas. A proper and step wise approach using clinical, radiological and histopathology is important to Diagnose and plan surgical management. Proper understanding of the proximity of adjacent structures and the high vascularity of the tumor.
Because of the rarity and under reporting of hibernomas they are often misdiagnosed as large lipomas or malignant soft tissue tumors, underscoring the importance of histopathology in ensuring accurate diagnosis and anticipating intraoperative. Careful dissection and ligation of the vasculature with the understanding of adjacent anatomy are key to safe tumor excision.
冬眠瘤是一种罕见的、生长缓慢、无痛的软组织良性肿瘤,由残留的褐色脂肪细胞发展而来,好发于胎儿和婴儿褐色脂肪较多的部位。由于该肿瘤罕见,常被忽视或误诊为其他病理情况,如脂肪肉瘤。
我们按照2020年CARE标准描述了一名26岁男性,其大腿出现疼痛性肿胀。未增强的磁共振成像检查显示股动脉内侧大腿中部有一个肿块。从其大腿获取活检标本进行组织病理学分析,结果提示为冬眠瘤。进行了广泛切除,结果显示股神经在肿块外侧,由于肿块效应神经走行改变。将肿块送去做组织病理学检查,结果与冬眠瘤一致。术后两周,患者报告疼痛强度明显减轻,术后六个月,他报告疼痛完全缓解。
冬眠瘤是不常见的良性肿瘤,通常无痛,但肿瘤可长得很大且靠近重要结构,这可以解释一些冬眠瘤出现症状的趋势。采用临床、放射学和组织病理学的正确且逐步的方法对于诊断和规划手术治疗很重要。要正确了解相邻结构的毗邻关系以及肿瘤的高血管性。
由于冬眠瘤罕见且报告不足,它们常被误诊为大脂肪瘤或恶性软组织肿瘤,这突出了组织病理学在确保准确诊断和预测术中情况方面的重要性。在了解相邻解剖结构的情况下仔细解剖和结扎血管是安全切除肿瘤的关键。