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通过喷雾干燥法优化壳聚糖微胶囊包埋亚麻籽油。

Optimization of chitosan for microencapsulation of flaxseed oil through spray drying.

机构信息

Department of Fisheries and Aquaculture, University of Veterinary and Animal Sciences, Lahore, Pakistan.

Department of Wildlife and Ecology, University of Veterinary and Animal Sciences, Lahore, Pakistan.

出版信息

Pak J Pharm Sci. 2021 Jul;34(4(Supplementary)):1569-1575.

Abstract

The study is aimed to characterize the wall material chitosan in combination with maltodextrin for microencapsulation of flaxseed oil to enhance the delivery of polyunsaturated fatty acids in functional foods. Four formulations of water-based oil emulsions containing flaxseed oil were prepared, homogenized, and analyzed in terms of stability and viscosity. Resulting emulsions were spray dried and further evaluated physicochemically. Results revealed that total moisture content of spray dried microcapsules was in range of 3.1 ± 0.01-3.32 ± 0.04, while highest microencapsulation efficiency found for spray dried powder was 88.8 ± 1.45. Peroxide and anisidine value revealed high oxidative stability of dried powders during storage at room temperature as compared to bulk FO. Among the four formulations, formulation 3 was found to be highly efficient with high encapsulation efficiency and lower PV (3.93 ± 0.13) and AV (2.93 ± 0.21) value. Fatty acid profile was stable after 30 days and slight change observed in composition. Formulations with different concentration of chitosan has significant (p <0.05) impact on emulsion properties and oxidative stability values. It is concluded that spray dried flaxseed oil microcapsules prepared using chitosan as coating material enhance the stability and delivery of omega-3 fatty acids.

摘要

本研究旨在对壳聚糖和麦芽糊精的壁材进行特性描述,将其用于微胶囊化亚麻籽油,以增强功能性食品中多不饱和脂肪酸的递送。制备了四种含有亚麻籽油的水包油乳液配方,进行了均化,并就其稳定性和黏度进行了分析。所得乳液进行了喷雾干燥,并进一步进行了物理化学评估。结果表明,喷雾干燥微胶囊的总水分含量在 3.1±0.01-3.32±0.04 的范围内,而喷雾干燥粉末的最高包埋效率为 88.8±1.45。与散装 FO 相比,过氧化值和茴香胺值表明干燥粉末在室温下储存时具有较高的氧化稳定性。在这四种配方中,配方 3 的包埋效率高,且具有较低的过氧化物值(3.93±0.13)和茴香胺值(2.93±0.21)。脂肪酸谱在 30 天后保持稳定,仅观察到组成上的轻微变化。具有不同壳聚糖浓度的配方对乳液性质和氧化稳定性值有显著影响(p<0.05)。结论是,使用壳聚糖作为包埋材料制备的喷雾干燥亚麻籽油微胶囊可增强 ω-3 脂肪酸的稳定性和递送。

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