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艾滋病合并卡波西肉瘤患者接触染发剂和多氯代二苯并对二噁英的流行病学调查

Exposure to hair dyes and polychlorinated dibenzo-p-dioxins in AIDS patients with Kaposi sarcoma: an epidemiological investigation.

作者信息

Hardell L, Moss A, Osmond D, Volberding P

机构信息

School of Public Health, University of California, Berkeley 94720.

出版信息

Cancer Detect Prev Suppl. 1987;1:567-70.

PMID:3480068
Abstract

Fifty male AIDS patients with Kaposi sarcoma and 50 matched controls were interviewed about occupation, exposure to pesticides, Vietnam service, smoking habits, etc. No difference in use of pesticides was seen. One case but no control had served in Vietnam and was thereby exposed to agent orange. Dioxins are known to be immunosuppressive in animals. No significant difference in exposure to dioxin-containing products was found between cases and controls, however. Of interest was the fact that four cases but no control were occupationally exposed to hair dyes, some of which have been reported to be carcinogenic.

摘要

对50名患有卡波西肉瘤的男性艾滋病患者和50名匹配的对照者进行了访谈,询问他们的职业、接触杀虫剂情况、是否去过越南服役、吸烟习惯等。在杀虫剂使用方面未发现差异。有一名患者曾在越南服役并因此接触过橙剂,而对照者中无人有此经历。已知二恶英对动物具有免疫抑制作用。然而,病例组和对照组在接触含二恶英产品方面未发现显著差异。有趣的是,有4名患者有职业性接触染发剂的情况,而对照者中无人有此情况,据报道某些染发剂具有致癌性。

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