Division of Pediatric Neurosurgery, Johns Hopkins Hospital, 600 N Wolfe Street, Phipps 556, Baltimore, MD 21287, USA.
Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, 6th Floor #A6600, Los Angeles, CA 90048, USA. Electronic address: https://twitter.com/AlonKashanian.
Neurosurg Clin N Am. 2022 Jan;33(1):25-35. doi: 10.1016/j.nec.2021.09.011.
Much of the current medical discussion for within centers for skeletal dysplasia and specifically patients with achondroplasia focuses on infancy and early childhood. Most neurosurgical concerns arise due to a defect in the endochondral ossification, resulting on early fusion of the synchondrosis. As patients age, the neurosurgical focus shifts from primarily cranial to spinal concerns. Often pediatric neurosurgeons may continue to follow their patients with skeletal dysplasia. However, general adult neurosurgeons and orthopedic surgeons may see these graduated adults in their practice. This article provides a review of the common neurosurgical concerns for patients with achondroplasia.
目前，骨骼发育不良中心，特别是软骨发育不全患者的医学讨论大多集中在婴儿期和幼儿期。大多数神经外科问题是由于软骨内骨化的缺陷引起的，导致骺板过早融合。随着患者年龄的增长，神经外科的关注点从主要的颅内向脊柱问题转移。儿科神经外科医生通常会继续关注他们的骨骼发育不良患者。然而，普通的成人神经外科医生和骨科医生可能会在他们的实践中看到这些成年患者。本文综述了软骨发育不全患者常见的神经外科问题。
