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年龄会改变乙醇对行为的影响:对青春期、成年期和老年期大鼠的研究。

Age modifies the effect of ethanol on behavior: Investigations in adolescent, adult and aged rats.

作者信息

Matthews D B, Imhoff B M

机构信息

Department of Psychology, University of Wisconsin - Eau Claire, Eau Claire, WI, United States.

Department of Psychology, University of Wisconsin - Eau Claire, Eau Claire, WI, United States.

出版信息

Int Rev Neurobiol. 2022;161:251-275. doi: 10.1016/bs.irn.2021.06.010. Epub 2021 Aug 3.

DOI:10.1016/bs.irn.2021.06.010
PMID:34801171
Abstract

The number of older people is increasing in most if not all countries in the world. In addition, the amount of alcohol consumption in the aged population is increasing and the consumption pattern is often in a binge fashion. However, little is known if the effects of alcohol, either acute or chronic exposure, vary in the older population compared to younger populations. The current mini-review will provide an overview of the effects of acute and chronic ethanol exposure at three different periods of development: adolescent, adult and aged on multiple different commonly studied behaviors. The overall conclusion is that biological age of the subject is a critical factor in understanding the effects of ethanol across the lifespan.

摘要

世界上大多数(即便不是所有)国家的老年人数量都在增加。此外,老年人群体中的酒精消费量在上升,且饮酒模式往往呈暴饮状态。然而,与年轻人群体相比,无论是急性还是慢性接触酒精,其在老年人群体中的影响是否有所不同,目前仍知之甚少。本综述将概述在发育的三个不同阶段(青少年期、成年期和老年期)急性和慢性乙醇接触对多种不同的常见研究行为的影响。总体结论是,个体的生物学年龄是理解乙醇在整个生命周期中影响的关键因素。

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