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经导管三尖瓣介入治疗:现有器械及相关证据。

Transcatheter tricuspid valve interventions: Current devices and associated evidence.

机构信息

Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada.

Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada; Hospital Clínic Barcelona, Barcelona, Spain.

出版信息

Prog Cardiovasc Dis. 2021 Nov-Dec;69:89-100. doi: 10.1016/j.pcad.2021.11.007. Epub 2021 Nov 19.

Abstract

Tricuspid regurgitation (TR) is a common finding in patients with chronic cardiopathy, and often a marker of an advanced disease. Being silent or with symptoms intertwined with the primitive left heart disease, TR has often been neglected, leading to the late referral of patients with advanced right-heart failure. Hence, isolated tricuspid surgery has been associated with high morbidity and mortality rates, the worse of all valve interventions, and medical management has been limited to symptomatic treatment. In this context, percutaneous therapies for severe TR have gained traction, addressing the unmet therapeutic gap for a less invasive disease-modifying management. The aim of this review is to provide an updated overview on transcatheter tricuspid valve interventions, focusing on devices' characteristics, associated evidence, and future perspectives.

摘要

三尖瓣反流(TR)是慢性心脏病患者的常见发现,通常是疾病晚期的标志。由于TR 可能无症状或与原发性左心疾病症状交织,因此常常被忽视,导致晚期右心衰竭患者转诊。因此,孤立的三尖瓣手术与高发病率和死亡率相关,是所有瓣膜介入中最差的,药物治疗仅限于对症治疗。在此背景下,针对严重 TR 的经皮治疗受到关注,为一种微创的疾病修正管理方法提供了治疗缺口。本综述的目的是提供经导管三尖瓣瓣膜介入治疗的最新概述,重点介绍器械的特点、相关证据和未来前景。

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