Lebaron-Jacobs Laurence, Herrera-Reyes Eduardo
Fundamental Research Division at the French Atomic Energy Commission (CEA), Cadarache, Saint Paul Les Durance, France.
Health Division at the Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Fontenay-aux-Roses, France.
J Radiol Prot. 2022 Jan 19;42(1). doi: 10.1088/1361-6498/ac3bc2.
The medical management of radiation accidents manual on the acute radiation syndrome proposed a successful strategic approach to diagnosing and treating acute radiation syndrome: the response category concept. Based on clinical and laboratory parameters, this approach aimed to assess damage to critical organ systems as a function of time, categorising different therapeutical approaches. After 20 years of its publication, the following paper attempts to provide a broad overview of this important document and tries to respond if proposed criteria are still relevant for the medical management of radiation-induced injuries. In addition, a critical analysis of its limitations and perspectives is proposed.
《急性放射综合征辐射事故医学处理手册》提出了一种诊断和治疗急性放射综合征的成功战略方法：反应类别概念。该方法基于临床和实验室参数，旨在评估关键器官系统随时间的损伤情况，并对不同的治疗方法进行分类。在该手册出版20年后，本文试图对这一重要文件进行全面概述，并探讨所提出的标准是否仍适用于辐射所致损伤的医学处理。此外，还对其局限性和前景进行了批判性分析。
