Galli Federica, Scotto Ludovica, Ravenda Simona, Zampino Maria Giulia, Pravettoni Gabriella, Mazzocco Ketti
Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology, IRCCS, Milan, Italy.
Department of Dynamic and Clinical Psychology, and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.
Front Psychol. 2021 Nov 3;12:590320. doi: 10.3389/fpsyg.2021.590320. eCollection 2021.
The role of personality in cancer incidence and development has been studied for a long time. As colorectal cancer (CRC) is one of the most prevalent cancer types and linked with lifestyle habits, it is important to better understand its psychological correlates, in order to design a more specific prevention and intervention plan. The aim of this systematic review is to analyze all the studies investigating the role of personality in CRC incidence. All studies on CRC and personality up to November 2020 were scrutinized according to the Cochrane Collaboration and the PRISMA statements. Selected studies were additionally evaluated for the Risk of Bias according to the Newcastle-Ottawa Scale (NOS). Eight studies met the inclusion criteria and were eventually included in this review. Two main constructs have been identified as potential contributors of CRC incidence: emotional regulation (anger) and relational style (egoism). Strong conclusions regarding the influence of personality traits on the incidence of CRC are not possible, because of the small number and the heterogeneity of the selected studies. Further research is needed to understand the complexity of personality and its role in the incidence of CRC and the interaction with other valuable risk factors.
人格在癌症发生和发展中的作用已被研究了很长时间。由于结直肠癌（CRC）是最常见的癌症类型之一，且与生活习惯有关，因此更好地了解其心理关联因素对于设计更具体的预防和干预计划非常重要。本系统评价的目的是分析所有调查人格在结直肠癌发病中作用的研究。根据Cochrane协作网和PRISMA声明，对截至2020年11月的所有关于结直肠癌和人格的研究进行了审查。根据纽卡斯尔-渥太华量表（NOS）对入选研究的偏倚风险进行了额外评估。八项研究符合纳入标准，最终被纳入本评价。已确定两个主要因素可能是结直肠癌发病的促成因素：情绪调节（愤怒）和人际关系风格（自我主义）。由于所选研究数量少且存在异质性，因此无法就人格特质对结直肠癌发病率的影响得出强有力的结论。需要进一步研究以了解人格的复杂性及其在结直肠癌发病中的作用，以及与其他重要风险因素的相互作用。
