Acupuncture and Tuina School/Acupuncture & Brain Science Research Center, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Acupuncture and Moxibustion Department, Beijing University of Chinese Medicine, Beijing, China.
Pain Res Manag. 2021 Nov 10;2021:9460695. doi: 10.1155/2021/9460695. eCollection 2021.
Acupuncture has been widely used as an alternative and complementary therapy for migraine. With the development of neuroimaging techniques, the central mechanism of acupuncture for migraine has gained increasing attention. This review aimed to analyze the study design and main findings of neuroimaging studies of acupuncture for migraine to provide the reference for future research. The original studies were collected and screened in three English databases (PubMed, Embase, and Cochrane Library) and four Chinese databases (Chinese National Knowledge Infrastructure, Chinese Biomedical Literature database, the Chongqing VIP database, and Wanfang database). As a result, a total of 28 articles were included. Functional magnetic resonance imaging was the most used neuroimaging technique to explore the cerebral activities of acupuncture for migraine. This review manifested that acupuncture could elicit cerebral responses on patients with migraine, different from sham acupuncture. The results indicated that the pain systems, including the medial pain pathway, lateral pain pathway, and descending pain modulatory system, participated in the modulation of the cerebral activities of migraine by acupuncture.
针灸作为偏头痛的一种替代和补充疗法已被广泛应用。随着神经影像学技术的发展，针灸治疗偏头痛的中枢机制越来越受到关注。本综述旨在分析针灸治疗偏头痛的神经影像学研究的设计和主要发现，为未来的研究提供参考。原始研究在三个英文数据库（PubMed、Embase 和 Cochrane Library）和四个中文数据库（中国知网、中国生物医学文献数据库、重庆维普数据库和万方数据库）中进行了收集和筛选。结果共纳入 28 篇文章。功能磁共振成像（fMRI）是最常用于探索针灸治疗偏头痛的大脑活动的神经影像学技术。本综述表明，针灸可以引起偏头痛患者的大脑反应，与假针灸不同。结果表明，疼痛系统，包括内侧疼痛通路、外侧疼痛通路和下行疼痛调制系统，参与了针灸对偏头痛大脑活动的调节。
